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Yezli, Saber, Shibl, Atef M., Livermore, David M. 
ORCID: https://orcid.org/0000-0002-9856-3703 and Memish, Ziad A.
(2012)
Antimicrobial resistance among Gram-positive pathogens in Saudi Arabia.
Journal of Chemotherapy, 24 (3).
pp. 125-136.
ISSN 1973-9478
Abstract
Several species of Gram-positive cocci are major nosocomial or community pathogens associated with morbidity and mortality. Here, we review the antimicrobial resistance among these pathogens in Saudi Arabia. In the last decades, antimicrobial resistance has increased among Staphylococcus aureus in the Kingdom with a growing prevalence of both nosocomial and community methicillin-resistant S. aureus (MRSA) isolates. As yet, no vancomycin-resistant MRSA have been reported, although isolates with reduced susceptibility to the drug have been noted. Currently, the prevalence of vancomycin-resistant entrococci (VRE) is low; however, VRE has been described in the Kingdom as well as Enterococcus faecalis and E. faecium isolates with high-level resistance to penicillin, sulfamethoxazole, macrolides, tetracycline, and aminoglycosides. In recent decades, the prevalence and rate of penicillin resistance and non-susceptibility among Streptococcus pneumoniae isolates have increased in Saudi Arabia. The organism remains, however, susceptible to other beta-lactams and to quinolones. On the other hand, resistance to co-trimoxazole and tetracyclines is high and resistance to macrolides is on the increase.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) |
| Depositing User: | Sophie Buckingham |
| Date Deposited: | 05 Mar 2013 10:50 |
| Last Modified: | 24 Jan 2024 01:19 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/41714 |
| DOI: | 10.1179/1973947812Y.0000000010 |
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