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Memish, Ziad A., Shibl, Atef M., Kambal, Abdelmageed M., Ohaly, Yazid A., Ishaq, Abdulrahman and Livermore, David M. 
ORCID: https://orcid.org/0000-0002-9856-3703
(2012)
Antimicrobial resistance among non-fermenting Gram-negative bacteria in Saudi Arabia.
Journal of Antimicrobial Chemotherapy, 67 (7).
pp. 1701-1705.
ISSN 0305-7453
Abstract
Objectives: Non-fermentative Gram-negative bacilli (non-fermenters) can cause serious healthcare-associated infections and are often resistant to multiple antibiotics. We examined resistance rates among these bacteria from different regions of Saudi Arabia. Methods: A cross-sectional study between January and December 2009 examined 8908 clinical non-fermenters from 24 hospitals across Saudi Arabia. Susceptibility testing was monitored to ensure compliance with CLSI guidelines, but the antibiotics tested were at the hospitals’ discretion. Results: Out of the 8908 non-fermenters, most were Pseudomonas aeruginosa (72.9%), followed by Acinetobacter baumannii (25.3%) and Stenotrophomonas maltophilia (1.8%). Resistance rates among P. aeruginosa were: polymyxin B, 2.2%; imipenem, 15.9%; ciprofloxacin, 22.0%; amikacin, 22.9%; and gentamicin, 31.2%. Resistance rates among A. baumannii were: imipenem, 5.4%; polymyxin B, 13.2%; ciprofloxacin, 64.0%; trimethoprim/sulfamethoxazole, 73.8%; amikacin, 76.9%; and gentamicin, 77.8%. Resistance rates among S. maltophilia were: polymyxin B, 6.9%; trimethoprim/sulfamethoxazole, 20.5%; and ciprofloxacin, 38.9%. There was major variation in resistance rates between geographical regions. Conclusions: Resistance rates among non-fermenters were high in Saudi Arabia and were variable among regions.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health |
| Depositing User: | Sophie Buckingham |
| Date Deposited: | 05 Mar 2013 10:55 |
| Last Modified: | 02 Feb 2024 01:36 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/41708 |
| DOI: | 10.1093/jac/dks091 |
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