Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

Lenk, Karsten, Palus, Sandra, Schur, Robert, Datta, Rakesh, Dong, Jesse, Culler, Michael D., Anker, Stefan, Springer, Jochen, Schuler, Gerhard and Adams, Volker (2013) Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model. Journal of Cachexia, Sarcopenia and Muscle, 4 (1). pp. 63-69. ISSN 2190-5991

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Abstract

In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Jochen Springer
Date Deposited:	29 Apr 2013 14:31
Last Modified:	23 Oct 2022 00:03
URI:	https://ueaeprints.uea.ac.uk/id/eprint/41639
DOI:	10.1007/s13539-012-0085-3

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