Diets containing pistachios reduce systolic blood pressure and peripheral vascular responses to stress in adults with dyslipidemia

West, Sheila G., Gebauer, Sarah K., Kay, Colin D., Bagshaw, Deborah M., Savastano, David M., Diefenbach, Christopher and Kris-Etherton, Penny M. (2012) Diets containing pistachios reduce systolic blood pressure and peripheral vascular responses to stress in adults with dyslipidemia. Hypertension, 60 (1). pp. 58-63. ISSN 0194-911X

Full text not available from this repository.

Abstract

Nut consumption reduces cardiovascular risk, and reductions in blood pressure and peripheral vascular resistance may be important mediators of this relationship. We evaluated effects of pistachios on flow-mediated dilation and blood pressure response to acute stress. Twenty-eight adults with dyslipidemia completed a randomized, crossover, controlled-feeding study. All of the meals were provided and calories were controlled. After 2 weeks on a typical Western diet (35% total fat and 11% saturated fat), test diets were presented in counterbalanced order for 4 weeks each, a low-fat control diet (25% total fat and 8% saturated fat), a diet containing 10% of energy from pistachios (on average, 1 serving per day; 30% total fat and 8% saturated fat), and a diet containing 20% of energy from pistachios (on average, 2 servings per day, 34% total fat and 8% saturated fat). None of the resting hemodynamic measures significantly differed from pretreatment values. When resting and stress levels were included in the repeated-measures analysis, average reductions in systolic blood pressure were greater after the diet containing 1 serving per day versus 2 servings per day of pistachios (mean change in systolic blood pressure, −4.8 vs −2.4 mm Hg, respectively; P<0.05). After the higher dose, there were significant reductions in peripheral resistance (−62.1 dyne·s×cm−5) and heart rate (−3 bpm) versus the control diet (P<0.0001). These changes were partially offset by increases in cardiac output. There was no effect of diet on fasting flow-mediated dilation. Reductions in peripheral vascular constriction and the resulting decrease in hemodynamic load may be important contributors to lower risk in nut consumers.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Colin Kay
Date Deposited:	17 Apr 2013 11:12
Last Modified:	16 May 2024 15:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/39467
DOI:	10.1161/HYPERTENSIONAHA.111.182147

Actions (login required)

View Item