Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene

Redshaw, Carl, Elsegood, Mark R. J., Wright, Joseph A. ORCID: https://orcid.org/0000-0001-9603-1001, Baillie-Johnson, Hugo, Yamato, Takehiko, De Giovanni, Stephen and Mueller, Anja ORCID: https://orcid.org/0000-0003-0774-0434 (2012) Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene. Chemical Communications, 48 (8). pp. 1129-1131. ISSN 1359-7345

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Abstract

Vanadyl bearing calix[4]arene ligands have undergone evaluation against several cell lines, and show varying degrees of toxicity. For vanadyl complexed to a sulfonylcalix[4]arene, monitoring of the strong blue fluorescence revealed slow uptake kinetics. The complex is exclusively found in the cytoplasm of the cells and uptake is not due to active endocytotic mechanisms.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024) Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017) Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Molecular and Tissue Pharmacology Faculty of Science > Research Groups > Chemistry of Light and Energy Faculty of Science > Research Groups > Energy Materials Laboratory
Depositing User:	Rhiannon Harvey
Date Deposited:	14 Mar 2012 15:04
Last Modified:	24 Sep 2024 08:52
URI:	https://ueaeprints.uea.ac.uk/id/eprint/38281
DOI:	10.1039/C2CC16480A

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