A novel fluorescent probe for NAD-consuming enzymes

Pergolizzi, Giulia, Butt, Julea N. ORCID: https://orcid.org/0000-0002-9624-5226, Bowater, Richard P. ORCID: https://orcid.org/0000-0002-2745-7807 and Wagner, Gerd K. (2011) A novel fluorescent probe for NAD-consuming enzymes. Chemical Communications, 47 (47). pp. 12655-12657. ISSN 1359-7345

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Abstract

A novel, fluorescent NAD derivative is processed as substrate by three different NAD-consuming enzymes. The new probe has been used to monitor enzymatic activity in a continuous format by changes in fluorescence and, in one case, to directly visualize alternative reaction pathways.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy (former - to 2024) Faculty of Science > School of Biological Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Molecular Microbiology Faculty of Science > Research Groups > Energy Materials Laboratory (former - to 2025) Faculty of Science > Research Groups > Chemistry of Light and Energy (former - to 2025) Faculty of Science > Research Groups > Chemistry of Life Processes (former - to 2025) Faculty of Science > Research Centres > Centre for Molecular and Structural Biochemistry Faculty of Science > Research Groups > Biophysical Chemistry (former - to 2017) Faculty of Science > Research Groups > Biosciences Teaching and Education Research Faculty of Science > Research Groups > Wolfson Centre for Advanced Environmental Microbiology
Depositing User:	Users 2731 not found.
Date Deposited:	13 Dec 2011 11:48
Last Modified:	18 Jun 2026 14:53
URI:	https://ueaeprints.uea.ac.uk/id/eprint/35716
DOI:	10.1039/c1cc15499k

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