Murine gammadelta T cells in infections: beneficial or deleterious?

Andrew, Elizabeth M and Carding, Simon R (2005) Murine gammadelta T cells in infections: beneficial or deleterious? Microbes and Infection, 7 (3). pp. 529-536. ISSN 1286-4579

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Abstract

Although the importance of gammadelta T cells in pathogen-induced immune responses is becoming increasingly apparent, it is not clear that their involvement is always of benefit to the host. Here we review evidence for the protective and damaging roles of gammadelta T cells in infection and discuss how these disparate findings might be resolved by considering the nature and properties of the pathogen, the sites of infection and conditions under which gammadelta T cell responses are initiated, and the involvement of different subsets of gammadelta T cells.

Item Type:	Article
Uncontrolled Keywords:	animals,gene expression,infection,inflammation,mice,t-lymphocyte subsets
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Rhiannon Harvey
Date Deposited:	14 Jul 2011 10:26
Last Modified:	27 Feb 2023 17:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/33710
DOI:	10.1016/j.micinf.2004.12.010

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