Synthesis of an isomer of the oxaspirobicyclic tetronic acid unit of the CCK-B receptor antagonist tetronothiodin

Bulman Page, Philip C., Vahedi, Hooshang, Batchelor, Kevin J., Hindley, Stephen, Edgar, Mark and Beswick, Paul (2003) Synthesis of an isomer of the oxaspirobicyclic tetronic acid unit of the CCK-B receptor antagonist tetronothiodin. Synlett (7). pp. 1022-1024. ISSN 0936-5214

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Abstract

An isomer of the oxaspirobicyclic tetronic acid unit of the CCK-B Receptor antagonist tetronothiodin, diastereoisomeric at the spiro centre, has been synthesized in five steps from dienol 4.

Item Type:	Article
Uncontrolled Keywords:	top-half,dieckmann,streptomyces sp-nr0489,tetronothiodin,cck,chlorothricolide,cholecystokinin,spiro tetronic acid,diels-alder
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemistry of Materials and Catalysis
Depositing User:	Rachel Smith
Date Deposited:	21 Jun 2011 09:41
Last Modified:	27 Oct 2025 23:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/32850
DOI:	10.1055/s-2003-39287

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