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ToolsBulman Page, Philip C., McKenzie, Michael J. and Gallagher, James A. (2002) Simple synthesis of oxiranylidene-2,2-bis(phosphonic acid): Tetrabenzyl geminal bisphosphonate esters as useful intermediates. Synthetic Communications, 32 (2). pp. 211-218. ISSN 0039-7911
Full text not available from this repository.Abstract
Tetrabenzyl geminal bisphosphonate esters are shown to be useful synthetic equivalents of 1,1-bis(phosphonic acid)s which may be easily functionalized at the central carbon atom without phosphonate ester hydrolysis. The parent bis(phosphonic acid) unit is readily regenerated by hydrogenolysis. The chemistry is used to prepare the elusive epoxide oxiranylidene-2,2-bis(phosphonic acid) by a short and reliable procedure.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | inhibitor,breast-cancer,agents,osteoporosis,bone-resorption,analogs,ovariectomized rats,postmenopausal women,mechanisms,osteoblasts,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Science > School of Chemistry (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemistry of Materials and Catalysis |
| Depositing User: | Rachel Smith |
| Date Deposited: | 21 Jun 2011 10:25 |
| Last Modified: | 24 Sep 2024 10:15 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/32840 |
| DOI: | 10.1081/SCC-120002004 |
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