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Ogborne, R. M., Rushworth, S. A., Charalambos, C. A. and O'Connell, M. A. 
ORCID: https://orcid.org/0000-0002-0267-0951
(2004)
Haem oxygenase-1: a target for dietary antioxidants.
Biochemical Society Transactions, 32 (6).
pp. 1003-1005.
ISSN 0300-5127
Abstract
HO-1 (haem oxygenase-1) is a stress-response enzyme involved in the catabolism of haem. in animal models, it plays a key protective role in vascular disease. HO-1 has anti-inflammatory effects in macrophages and is induced by a range of stimuli, including antioxidants, in various cell types. As dietary antioxidants are considered to be beneficial in vascular disease, their protective effects may occur through induction of HO-1. Emerging evidence suggests that a range of dietary and other naturally occurring antioxidants stimulate HO-1 expression in various cell types, although regulation by these compounds has not been investigated in detail. These studies suggest that HO-1 may be a target for dietary therapy in vascular disease.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Pharmacy (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017) Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies Faculty of Science > Research Groups > Molecular and Tissue Pharmacology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health |
| Depositing User: | Rachel Smith |
| Date Deposited: | 06 Jun 2011 12:11 |
| Last Modified: | 24 Sep 2024 10:06 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/31784 |
| DOI: | 10.1042/BST0321003 |
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