Influence of the APOC3 −2854T>G polymorphism on plasma lipid levels: effect of age and gender

Minihane, Anne Marie ORCID: https://orcid.org/0000-0001-9042-4226, Finnegan, Yvonne E., Talmud, Philippa, Leigh-Firbank, Elizabeth C. and Williams, Christine M. (2002) Influence of the APOC3 −2854T>G polymorphism on plasma lipid levels: effect of age and gender. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1583 (3). pp. 311-314.

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Abstract

The APOC3 −2854T>G polymorphism lies in the APOC3–A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype–triglyceride interactions.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User: Rhiannon Harvey
Date Deposited: 01 Jun 2011 10:05
Last Modified: 19 Oct 2023 01:01
URI: https://ueaeprints.uea.ac.uk/id/eprint/31673
DOI: 10.1016/S1388-1981(02)00264-0

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