Efficient gene transfection with functionalised multicalixarenes

Lalor, R., DiGesso, J. L., Mueller, A. ORCID: https://orcid.org/0000-0003-0774-0434 and Matthews, S. E. (2007) Efficient gene transfection with functionalised multicalixarenes. Chemical Communications (46). pp. 4907-4909. ISSN 1359-7345

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Abstract

Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.

Item Type:	Article
Uncontrolled Keywords:	binding-properties,conformational,calixarenes,dendrimers,dna,ion-channel,upper rim,solid lipid nanoparticles,isomers,chemokine receptor ccr5,delivery
Faculty \ School:	Faculty of Science > School of Pharmacy (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017) Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021) Faculty of Science > Research Groups > Molecular and Tissue Pharmacology (former - to 2025) Faculty of Science > Research Groups > Pharmacology and Biological Chemistry
Depositing User:	Rachel Smith
Date Deposited:	26 May 2011 10:40
Last Modified:	18 Jun 2026 15:24
URI:	https://ueaeprints.uea.ac.uk/id/eprint/31453
DOI:	10.1039/b712100h

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