Efficient gene transfection with functionalised multicalixarenes

Lalor, R., DiGesso, J. L., Mueller, A. ORCID: https://orcid.org/0000-0003-0774-0434 and Matthews, S. E. ORCID: https://orcid.org/0000-0001-8821-0851 (2007) Efficient gene transfection with functionalised multicalixarenes. Chemical Communications (46). pp. 4907-4909. ISSN 1359-7345

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Abstract

Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.

Item Type: Article
Uncontrolled Keywords: binding-properties,conformational,calixarenes,dendrimers,dna,ion-channel,upper rim,solid lipid nanoparticles,isomers,chemokine receptor ccr5,delivery
Faculty \ School: Faculty of Science > School of Pharmacy
UEA Research Groups: Faculty of Science > Research Groups > Pharmaceutical Cell Biology (former - to 2017)
Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017)
Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021)
Faculty of Science > Research Groups > Molecular and Tissue Pharmacology
Depositing User: Rachel Smith
Date Deposited: 26 May 2011 10:40
Last Modified: 24 Oct 2022 01:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/31453
DOI: 10.1039/b712100h

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