Rotavirus genotyping: keeping up with an evolving population of human rotaviruses

Iturriza-Gómara, Miren, Kang, Gagandeep and Gray, Jim (2004) Rotavirus genotyping: keeping up with an evolving population of human rotaviruses. Journal of Clinical Virology, 31 (4). pp. 259-265. ISSN 1873-5967

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Abstract

The use of molecular methods for rotavirus characterisation provides not only increased sensitivity for typing, but also allows accurate and more complete characterisation of strains, and the identification of putative reassortant strains. However, due to the constant accumulation of point mutations through genetic drift, and to the emergence of novel genotypes, possibly zoonotic transmission and subsequent reassortment, the reagents and methods used require close monitoring and updating. Methods and oligonucleotide primers are described to overcome failures to type G9, G10 and P[11] rotavirus strains, and cross-reactivity identified between G10 and G3 rotaviruses.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	Rhiannon Harvey
Date Deposited:	18 May 2011 15:41
Last Modified:	06 Mar 2023 15:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/30884
DOI:	10.1016/j.jcv.2004.04.009

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