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ToolsJothivasan, V. K. and Hamilton, C. J. (2008) Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes. Natural Product Reports, 25 (6). pp. 1091-1117. ISSN 0265-0568
Full text not available from this repository.Abstract
Actinomycetes produce mycothiol as their major low molecular weight thiol, which parallels the functions of glutathione found in prokaryotes and most Gram-negative bacteria. This review covers progress that has so far been made in terms of its distribution, biosynthesis and metabolic functions, as well as chemical syntheses of mycothiol and alternative substrates and inhibitors of mycothiol biosynthesis and mycothiol-dependent enzymes. 152 references are cited.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | inositol monophosphatase,inhibitor,dependent formaldehyde dehydrogenase,reductase,disulfide,cysteine ligase mshc,dibromotyrosine alkaloid,s-conjugate amidase,corynebacterium-glutamicum,anti-sigma factor,streptomyces-coelicolor a3(2),mycobacterium-tuberculosis erdman,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Science > School of Pharmacy (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Medicinal Chemistry (former - to 2017) Faculty of Science > Research Groups > Chemical Biology and Medicinal Chemistry (former - to 2021) |
| Depositing User: | Rachel Smith |
| Date Deposited: | 18 May 2011 09:32 |
| Last Modified: | 24 Sep 2024 09:33 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/30708 |
| DOI: | 10.1039/b616489g |
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