Monitoring vaccine safety using case series cumulative sum charts

Musonda, Patrick, Hocine, Mounia N., Andrews, Nick J., Tubert-Bitter, Pascale and Farrington, C. Paddy (2008) Monitoring vaccine safety using case series cumulative sum charts. Vaccine, 26 (42). pp. 5358-5367. ISSN 1873-2518

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Abstract

We adapt the self-controlled case series method for routine surveillance of vaccine safety using cumulative sum (CUSUM) charts. The CUSUM surveillance method we propose is applicable for detecting associations that arise in a short pre-determined risk period following vaccination. The performance of the case series CUSUM is investigated through simulations. We illustrate the method using retrospective analyses of influenza vaccine and Bell's palsy, and MMR vaccine and febrile convulsions.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	Rhiannon Harvey
Date Deposited:	11 May 2011 15:11
Last Modified:	24 Jan 2023 10:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/30259
DOI:	10.1016/j.vaccine.2008.08.010

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