Photosensitizer efficacy of non-peripheral substituted alkylbenzopyridoporphyrazines for photodynamic therapy of cancer

Sakamoto, Keiichi, Kato, Taku, Kawaguchi, Tomomi, Ohno-Okumura, Eiko, Urano, Toshiyuki, Yamaoka, Tsuguo, Suzuki, Shota and Cook, Michael J. (2002) Photosensitizer efficacy of non-peripheral substituted alkylbenzopyridoporphyrazines for photodynamic therapy of cancer. Journal of Photochemistry and Photobiology A: Chemistry, 153 (1-3). pp. 245-252. ISSN 1010-6030

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Abstract

The triplet state of zinc non-peripheral substituted alkylbenzopyridoporphyrazines and position isomers were measured, using laser-flash photolysis in poly(methyl methacrylate) film. The triplet lifetime increased with an increasing pyridine number in the molecule. The lowest symmetric isomer having two pyridine rings in the molecule showed the longest triplet state lifetime. The compound was suitable for the use the photosensitizer as a photodynamic therapy of cancer. (C) 2002 Elsevier Science B.V. All rights reserved.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
Depositing User:	Rachel Smith
Date Deposited:	10 May 2011 13:48
Last Modified:	24 Sep 2024 10:19
URI:	https://ueaeprints.uea.ac.uk/id/eprint/30127
DOI:	10.1016/S1010-6030(02)00292-7

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