Guo, Z. X., Cammidge, A. N. ORCID: https://orcid.org/0000-0001-7912-4310 and Horwell, D. C.
(2000)
A convenient and versatile method for the synthesis of protected guanidines.
Synthetic Communications, 30 (16).
pp. 2933-2943.
ISSN 0039-7911
Abstract
Aromatic, aliphatic and sterically hindered amines react smoothly with commercially available N,N'-bis-BOC-S-methylisothiourea 2 in the presence of mercury chloride to give the protected guanidine in good yield. It is particularly noteworthy that 2 can also be employed in a straightforward, two-step synthesis of monoaryl internal guanidines.
Item Type: | Article |
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Faculty \ School: | Faculty of Science > School of Chemistry |
Depositing User: | Rachel Smith |
Date Deposited: | 09 May 2011 14:58 |
Last Modified: | 12 May 2023 09:31 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/30056 |
DOI: |
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