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Guo, Zhao-Xia, Cammidge, Andrew N. 
ORCID: https://orcid.org/0000-0001-7912-4310 and Horwell, David C.
(2000)
A convenient and versatile method for the synthesis of protected guanidines.
Synthetic Communications, 30 (16).
pp. 2933-2943.
ISSN 0039-7911
Abstract
Aromatic, aliphatic and sterically hindered amines react smoothly with commercially available N,N'-bis-BOC-S-methylisothiourea 2 in the presence of mercury chloride to give the protected guanidine in good yield. It is particularly noteworthy that 2 can also be employed in a straightforward, two-step synthesis of monoaryl internal guanidines.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Science > School of Chemistry (former - to 2024) |
| UEA Research Groups: | Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Chemistry of Light and Energy Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017) |
| Depositing User: | Rachel Smith |
| Date Deposited: | 09 May 2011 14:58 |
| Last Modified: | 24 Sep 2024 10:27 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/30056 |
| DOI: | 10.1080/00397910008087443 |
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