Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy

Kiesslich, Ralf, Goetz, Martin, Angus, Elizabeth M, Hu, Qiuping, Guan, Yanfang, Potten, Chris, Allen, Terry, Neurath, Markus F, Shroyer, Noah F, Montrose, Marshall H and Watson, Alastair J M ORCID: https://orcid.org/0000-0003-3326-0426 (2007) Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy. Gastroenterology, 133 (6). pp. 1769-1778. ISSN 1528-0012

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Abstract

Confocal endomicroscopy is an emerging technology that poses the endoscopist with challenges for identifying epithelial structures in the human intestine. We have shown previously that the murine intestinal epithelium is punctuated by gaps caused by cell shedding. The goals of this study were to determine if confocal endomicroscopy could resolve the presence of human epithelial gaps and whether a proinflammatory cytokine could increase cell shedding.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,aged,animals,colonoscopy,epithelial cells,female,humans,intestine, large,intestine, small,male,mice,microscopy, confocal,middle aged,tumor necrosis factor-alpha
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User:	Rhiannon Harvey
Date Deposited:	01 Apr 2011 09:21
Last Modified:	20 Aug 2023 00:33
URI:	https://ueaeprints.uea.ac.uk/id/eprint/27865
DOI:	10.1053/j.gastro.2007.09.011

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