Prevalence of undiagnosed prostate cancer in men with erectile dysfunction

Sairam, K., Kulinskaya, E., Boustead, G. B., Hanbury, D. C. and McNicholas, T. A. (2002) Prevalence of undiagnosed prostate cancer in men with erectile dysfunction. BJU International, 89 (3). pp. 261-263. ISSN 1464-4096

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Abstract

Objective: To explore the prevalence of prostate cancer in men presenting with erectile dysfunction (ED). Patients and methods: In a prospective study, 127 men with ED of at least 6months duration underwent screening for prostate cancer using prostate specific antigen (PSA) and a digital rectal examination (DRE). Men with a high PSA level (>4ng/mL) had sextant biopsies taken under sedoanalgesia. The serum testosterone level was measured in all the men. Results: Twenty-six men were aged <50 years and all had a normal PSA level; of 101 men aged >50 years, 20 had an abnormal PSA. The detection rate for prostate cancer using PSA and DRE was 5%, which was not significantly higher than in the general population. All the detected cancers were clinically significant (>T2a, Gleason grade >4). Two of the five men diagnosed with prostate cancer were Afro-Caribbean. Of the 127 men, 31% had a low serum testosterone level, but there was no association between testosterone and PSA levels. Conclusions: Prostate cancer is no more common in men with ED than in the normal male population. Therefore, routine screening for prostate cancer in men with ED is not indicated.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Computing Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Data Science and AI Faculty of Medicine and Health Sciences > Research Centres > Business and Local Government Data Research Centre (former - to 2023) Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Depositing User:	Vishal Gautam
Date Deposited:	28 Jul 2011 11:17
Last Modified:	14 Oct 2025 02:32
URI:	https://ueaeprints.uea.ac.uk/id/eprint/22138
DOI:	10.1046/j.1464-4096.2001.01271.x

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