A novel exploratory method for visual recombination detection

Strimmer, Korbinian, Forslund, Kristoffer, Holland, Barbara and Moulton, Vincent ORCID: https://orcid.org/0000-0001-9371-6435 (2003) A novel exploratory method for visual recombination detection. Genome Biology, 4. ISSN 1465-6906

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Abstract

A versatile visual approach for detecting recombination and identifying recombination breakpoints within a sequence alignment is presented. The method is based on two novel diagrams - the highway plot and the occupancy plot - that graphically portray phylogenetic inhomogeneity along an alignment, and can be viewed as a synthesis of two widely used but unrelated methods: bootscanning and quartet-mapping. To illustrate the method, simulated data and HIV-1 and influenza A datasets are investigated.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Computing Sciences
UEA Research Groups:	Faculty of Science > Research Groups > Computational Biology Faculty of Science > Research Groups > Computational Biology > Computational biology of RNA (former - to 2018) Faculty of Science > Research Groups > Computational Biology > Phylogenetics (former - to 2018) Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Depositing User:	Vishal Gautam
Date Deposited:	13 Jun 2011 12:38
Last Modified:	16 Jun 2023 23:43
URI:	https://ueaeprints.uea.ac.uk/id/eprint/21685
DOI:	10.1186/gb-2003-4-5-r33

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