Infectious titres of Emiliania huxleyi virus 86 are reduced by exposure to millimolar dimethyl sulfide and acrylic acid

Evans, Claire, Malin, Gillian ORCID: https://orcid.org/0000-0002-3639-9215, Wilson, William H. and Liss, Peter S. (2006) Infectious titres of Emiliania huxleyi virus 86 are reduced by exposure to millimolar dimethyl sulfide and acrylic acid. Limnology and Oceanography, 51 (5). pp. 2468-2471. ISSN 1939-5590

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Abstract

We examined the ability of dimethylsulfoniopropionate (DMSP), its cleavage products dimethyl sulfide (DMS) and acrylic acid (AA), and the oxidized form of DMS dimethylsulfoxide (DMSO), to inhibit infection of Emiliania huxleyi virus 86 (EhV-86). Infectivity was assessed by plaque assay of viral stock that had been exposed to these compounds. The initial concentrations of the compounds tested were 250 mmol L-1 for DMSP, DMS, and AA, and 14 mmol L-1 for DMSO. These are the maximum concentrations thought to occur in E. huxleyi and therefore the highest EhV-86 might encounter. DMSP and DMSO had no effect on EhV-86; however, both DMS and AA diminished viral titers. Further experiments established that both DMS and AA significantly reduced titers from a concentration of 100 mmol L-1 and that they had a greater antiviral effect when applied in combination. The DMSP system in algae could function as a chemical defense against viral infection that would benefit the surviving cells in the population by reducing infective titers of progeny viruses and therefore decreasing the probability of infection of further cells.

Item Type: Article
Faculty \ School: Faculty of Science > School of Environmental Sciences
UEA Research Groups: Faculty of Science > Research Groups > Centre for Ocean and Atmospheric Sciences
Faculty of Science > Research Centres > Centre for Ecology, Evolution and Conservation
Faculty of Science > Research Groups > Marine Knowledge Exchange Network
Faculty of Science > Research Groups > Collaborative Centre for Sustainable Use of the Seas
Faculty of Science > Research Groups > Environmental Biology
Faculty of Science > Research Groups > Resources, Sustainability and Governance (former - to 2018)
Faculty of Science > Research Groups > Marine and Atmospheric Sciences (former - to 2017)
Faculty of Science > Research Groups > Climate, Ocean and Atmospheric Sciences (former - to 2017)
Faculty of Science > Research Groups > Climatic Research Unit
Depositing User: Rosie Cullington
Date Deposited: 24 Jan 2011 15:13
Last Modified: 19 Mar 2024 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/19562
DOI: 10.4319/lo.2006.51.5.2468

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