Pain reporting at different body sites is explained by a single underlying genetic factor

Williams, Frances M. K., Spector, Tim D. and MacGregor, Alex J. ORCID: https://orcid.org/0000-0003-2163-2325 (2010) Pain reporting at different body sites is explained by a single underlying genetic factor. Rheumatology, 49 (9). pp. 1753-1755. ISSN 1462-0332

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Abstract

Musculoskeletal pain is reported commonly; however, the extent to which pain in individual body areas reflects the severity of site-specific pathology or a more generalized propensity to feel pain is uncertain. We used a classical twin design to examine the pattern of pain reporting at different body sites among monozygotic (MZ) and dizygotic (DZ) twins to assess its heritability and to examine evidence for a common underlying propensity to report musculoskeletal pain.

Item Type:	Article
Uncontrolled Keywords:	adolescent,adult,aged,aged, 80 and over,female,genetic predisposition to disease,humans,male,middle aged,multivariate analysis,osteoarthritis,pain,pain measurement,questionnaires,severity of illness index,twins,young adult
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Science > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:13
Last Modified:	04 Mar 2024 16:39
URI:	https://ueaeprints.uea.ac.uk/id/eprint/15341
DOI:	10.1093/rheumatology/keq170

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