Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites

Wang, Xia ORCID: https://orcid.org/0000-0001-6915-2588, Jobe, Momodou, Tyler, Kevin M. ORCID: https://orcid.org/0000-0002-0647-8158 and Steverding, Dietmar (2008) Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites. Parasites & Vectors, 1. ISSN 1756-3305

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Abstract

The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach (0.05% NaOCl) killed all three trypanosomatids. Ethanol and water destroyed the parasites within 5 min at concentrations of 15-17.5% and 80-90%, respectively. All three organisms were also killed when treated for 5 min at 50 degrees C. The results indicate that the disinfectants, water and temperature treatment (i.e. autoclaving) are suitable laboratory hygiene measures against trypanosomatid parasites.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Pathogen Biology Group
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:13
Last Modified:	17 Nov 2024 07:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/14998
DOI:	10.1186/1756-3305-1-35

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