Perspectives on the Trypanosoma cruzi-host cell receptor interaction

Villalta, Fernando, Scharfstein, Julio, Ashton, Anthony W., Tyler, Kevin M. ORCID: https://orcid.org/0000-0002-0647-8158, Guan, Fangxia, Mukherjee, Shankar, Lima, Maria F., Alvarez, Sandra, Weiss, Louis M., Huang, Huan, Machado, Fabiana S. and Tanowitz, Herbert B. (2009) Perspectives on the Trypanosoma cruzi-host cell receptor interaction. Parasitology Research, 104 (6). pp. 1251-1260.

Full text not available from this repository. (Request a copy)

Abstract

Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions. Some of the key receptors considered are those for thromboxane, bradykinin, and for the nerve growth factor TrKA. Other important receptors such as galectin-3, thrombospondin, and laminin are also discussed. Investigation into the molecular biology and cell biology of host receptors for T. cruzi may provide novel therapeutic targets.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Pathogen Biology Group
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:12
Last Modified:	24 Sep 2024 09:26
URI:	https://ueaeprints.uea.ac.uk/id/eprint/14995
DOI:	10.1007/s00436-009-1383-3

Actions (login required)

View Item