To freeze or not to freeze: a cost-effectiveness analysis of wart treatment

Keogh-Brown, M. R., Fordham, R. J. ORCID: https://orcid.org/0000-0002-5520-6255, Thomas, K. S., Bachmann, M. O. ORCID: https://orcid.org/0000-0003-1770-3506, Holland, R. C., Avery, A. J., Armstrong, S. J., Chalmers, J. R., Howe, A. C., Rodgers, S., Williams, H. C. and Harvey, I. M. (2007) To freeze or not to freeze: a cost-effectiveness analysis of wart treatment. British Journal of Dermatology, 156 (4). 687–692. ISSN 1365-2133

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Abstract

Background: Several general practitioner (GP)-prescribed and over-the-counter therapies for warts and verrucae are available. However, the cost-effectiveness of these treatments is unknown. Objectives: To compare the cost-effectiveness of different treatments for cutaneous warts. Methods: We designed a decision-analytic Markov simulation model based on systematic review evidence to estimate the cost-effectiveness of various treatments. The outcome measures studied are percentage of patients cured, cost of treatment and incremental cost-effectiveness ratio for each treatment, compared with no treatment, after 18 weeks. Results: Duct tape was most cost-effective but published evidence of its effectiveness is sparse. Salicylic acid was the most cost-effective over-the-counter treatment commonly used. Cryotherapy administered by a GP was less cost-effective than GP-prescribed salicylic acid and less cost-effective than cryotherapy administered by a nurse. Conclusions: Duct tape could be adopted as the primary treatment for cutaneous warts if its effectiveness is verified by further rigorous trials. Nurse-administered cryotherapy is likely to be more cost-effective than GP-administered cryotherapy.

Item Type: Article
Uncontrolled Keywords: cryotherapy,decision analysis,markov model,salicylic acid
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Health Economics
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care
Faculty of Medicine and Health Sciences > Research Centres > Population Health
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 21 Dec 2023 01:34
URI: https://ueaeprints.uea.ac.uk/id/eprint/14284
DOI: 10.1111/j.1365-2133.2007.07768.x

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