A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer

Tehrani, H., Walls, J., Price, G. M., Cotton, S., Sassoon, E. and Hall, P. (2006) A novel imaging technique as an adjunct to the in vivo diagnosis of nonmelanoma skin cancer. British Journal of Dermatology, 155 (6). pp. 1177-1183. ISSN 1365-2133

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Abstract

Background: Spectrophotometric intracutaneous analysis (SIAscopy) is a light‐based imaging system capable of producing rapid images of melanin, blood and collagen of the skin. Although the SIAscope has been investigated for melanoma diagnosis, no formal study has been conducted to determine its use in the diagnosis of nonmelanoma skin cancer (NMSC). Objectives: A prospective study was conducted to investigate the potential for the SIAscope to diagnose NMSC. Methods: In total, 302 consecutive patients were recruited into the study, 363 lesions being scanned. Logistic regression analysis was used to construct a predictive model for NMSC diagnosis and receiver–operator characteristic curves were used to assess overall accuracy of the model. Results: A sensitivity of 98·0%, specificity of 95·7% and overall accuracy of 98·2% was found for NMSC diagnosis by the SIAscope model. Conclusions: Results suggest that the SIAscope may be a useful adjunct in the diagnosis of NMSC.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care
Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Depositing User: EPrints Services
Date Deposited: 25 Nov 2010 11:11
Last Modified: 16 Jul 2024 14:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/13835
DOI: 10.1111/j.1365-2133.2006.07513.x

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