Genetic influences in the aetiology of tears of the rotator cuff: Sibling risk of a full-thickness tear

Harvie, P., Ostlere, S. J., Teh, J., McNally, E. G., Clipsham, K. E., Burston, B. J., Pollard, T. C. B. and Carr, A. J. (2004) Genetic influences in the aetiology of tears of the rotator cuff: Sibling risk of a full-thickness tear. Journal of Bone and Joint Surgery-British, 86-B (5). pp. 696-700.

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Abstract

From a retrospective, cohort study of 205 patients diagnosed with full-thickness tears of the rotator cuff, we determined, using ultrasound, the prevalence of such tears in their 129 siblings. Using 150 spouses as controls, the relative risk of full-thickness tears in siblings versus controls was 2.42 (95% CI 1.77 to 3.31). The relative risk of symptomatic full-thickness tears in siblings versus controls was 4.65 (95% CI 2.42 to 8.63). The significantly increased risk for tears in siblings implies that genetic factors play a major role in the development of full-thickness tears of the rotator cuff.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:09
Last Modified:	24 Sep 2024 10:04
URI:	https://ueaeprints.uea.ac.uk/id/eprint/12777
DOI:	10.1302/0301-620X.86B5.14747

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