Pragmatic research tales: The ELEVATE study as an illustration of the issues involved in implementing pragmatic research

Blyth, Annie, Musgrave, Stan, Price, David and Harvey, Ian (2003) Pragmatic research tales: The ELEVATE study as an illustration of the issues involved in implementing pragmatic research. Primary Care Respiratory Journal, 12 (3). p. 95. ISSN 1475-1534

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Abstract

Background: Despite increased asthma preventative treatment there is evidence that large numbers of patients continue to suffer significant symptoms and lifestyle limitation. Possible reasons include lack of disease recognition, poor adherence with inhaled corticosteroids and inability of inhaled steroids to fully control asthma.As earlier studies have been short term, and far from "real-life", the NHS' National Coordinating Centre for Health Technology Assessment sought a study to look at both the short and long term impact on quality of life, clinical status and resource utilisation of using leukotriene receptor antagonists (LTRAs). ELEVATE was conceived in response to this need and the GPIAG was successful in winning this research bid in conjunction with the University of East Anglia. Study objectives and design: The study's objective is to compare quality of life comparing LTRAs with alternative therapies at steps 2 & 3 of the National Asthma Guidelines for 720 adult patients. The study is a pragmatic randomised controlled trial over 2 years that will provide information about broadly generalisable patients in "real world" general practice.

Item Type:	Article
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Centres > Population Health
Depositing User:	EPrints Services
Date Deposited:	25 Nov 2010 11:09
Last Modified:	06 Jun 2024 14:41
URI:	https://ueaeprints.uea.ac.uk/id/eprint/12226
DOI:	10.1038/pcrj.2003.56

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