Pharmacist-independent prescriber deprescribing in UK care homes: Contextual factors associated with increased activity

Alharthi, Mohammed, Scott, Sion, Alldred, David Phillip, Holland, Richard, Hughes, Carmel, Birt, Linda, Blacklock, Jeanette, Bond, Christine, Clark, Allan and Wright, David (2023) Pharmacist-independent prescriber deprescribing in UK care homes: Contextual factors associated with increased activity. British Journal of Clinical Pharmacology, 89 (4). pp. 1509-1513. ISSN 0306-5251

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Abstract

Aims: The Care Home Independent Pharmacist Prescriber Study (CHIPPS) process evaluation hypothesized that contextual factors influenced the likelihood of deprescribing by pharmacist-independent prescribers. The aim of this paper is to test this hypothesis.  Methods: From CHIPPS study data, medications deprescribed totalled 284 for 370 residents in UK care homes. Regression analysis was used to describe the relationship between the number of medicines stopped and contextual factors (number of residents cared for, pharmacist employment within associated medical practice, previous care home experience, hours active within trial, years’ experience as a pharmacist and as a prescriber).  Results: Number of residents and pharmacist-independent prescriber employment within a medical practice were positive predictors of deprescribing.  Conclusion: Previous experiences were not related to deprescribing likelihood. Increasing the number of residents increases the opportunity for deprescribing and therefore this relationship is intuitive. The location within a medical practice is an interesting finding that requires further exploration to understand its exact nature.

Item Type:	Article
Additional Information:	Data Availability Statement: The analysed datasets used in the current study are available upon reasonable request from the corresponding author.
Uncontrolled Keywords:	deprescription,long-term care facilities,medication review,medicines optimization,nursing home,polypharmacy,residential home,pharmacology,pharmacology (medical) ,/dk/atira/pure/subjectarea/asjc/3000/3004
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Health Sciences Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	16 Jan 2026 13:30
Last Modified:	18 Jan 2026 07:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/101630
DOI:	10.1111/bcp.15643

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