Prions and neurodegenerative diseases

Hope, James (2000) Prions and neurodegenerative diseases. Current Opinion in Genetics and Development, 10 (5). pp. 568-574. ISSN 0959-437X

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Abstract

The long-term, progressive decay of the central nervous system typifies prion diseases, a group of rare, transmissible maladies affecting humans, sheep, cattle and some other types of mammal. Little is known about the early molecular events in its pathogenesis but the diverse roles of PrP, the prion protein, in its destructive action have recently been re-emphasised.

Item Type: Article
Uncontrolled Keywords: genetics,developmental biology ,/dk/atira/pure/subjectarea/asjc/1300/1311
Faculty \ School: Faculty of Science > School of Biological Sciences
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Depositing User: LivePure Connector
Date Deposited: 05 Dec 2025 13:30
Last Modified: 10 Dec 2025 14:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/101287
DOI: 10.1016/S0959-437X(00)00129-5

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