Amyloid and prions:Some biochemical investigations of cerebral amyloidosis in mice

Hope, James and Kirby, Louise (2012) Amyloid and prions:Some biochemical investigations of cerebral amyloidosis in mice. Folia Neuropathologica, 50 (1). pp. 13-19. ISSN 1641-4640

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Abstract

Prion-like transmission of protein aggregates or amyloid in several neurodegenerative diseases, such as Parkinson's disease, Huntington's disease and Alzheimer's disease, in addition to the transmissible spongiform encephalopathies (or prion diseases), has been proposed recently. This is a controversial idea and, in this paper, we consider what we mean by a "prion", and by "amyloid", and present some biochemical investigations of cerebral prion amyloidosis in mice.

Item Type:	Article
Uncontrolled Keywords:	alzheimer's disease,amyloid,cerebral amyloidosis,huntington's disease,mouse,parkinson's disease,prion,strains,time-resolved fluoroimmunoassay,transmissible spongiform encephalopathy,pathology and forensic medicine,clinical neurology ,/dk/atira/pure/subjectarea/asjc/2700/2734
Faculty \ School:	Faculty of Science > School of Biological Sciences
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	04 Dec 2025 12:30
Last Modified:	10 Dec 2025 14:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/101254
DOI:

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