Observations on the transmission of scrapie in experiments using embryo transfer

Foster, J. D., Hunter, N., Williams, A., Mylne, M. J. A., McKelvey, W. A. C., Hope, J., Fraser, H. and Bostock, C. (1996) Observations on the transmission of scrapie in experiments using embryo transfer. Veterinary Record, 138 (23). pp. 559-562. ISSN 0042-4900

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Abstract

This investigation studied the maternal transmission of scrapie in sheep by using embryo transfer to examine the viability of highly susceptible offspring derived from scrapie-affected and uninfected donors. The study also examined the effect of washing the embryos. Scrapie occurred in both washed and unwashed embryo-derived Sip sAsA progeny from both groups of donor ewes. As a result, the earlier observation that scrapie might pass via the unwashed embryo to develop as disease in adult sheep has to be reassessed. Several other implications of the work are considered, including the possibility that natural scrapie is not purely a genetic disease.

Item Type:	Article
Uncontrolled Keywords:	veterinary(all) ,/dk/atira/pure/subjectarea/asjc/3400
Faculty \ School:	Faculty of Science > School of Biological Sciences
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	28 Nov 2025 11:30
Last Modified:	10 Dec 2025 14:30
URI:	https://ueaeprints.uea.ac.uk/id/eprint/101129
DOI:	10.1136/vr.138.23.559

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