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Khonkarn, Ruttiros, Ramadani, Pranvera, Qi, Sheng 
ORCID: https://orcid.org/0000-0003-1872-9572, Ali, Tariq and Krokidis, Miltiadis
(2025)
Technology, pharmacology, and clinical outcomes of sirolimus coated balloons for peripheral arterial interventions.
Expert Review of Medical Devices, 22 (12).
pp. 1369-1378.
ISSN 1745-2422
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Abstract
Introduction: Peripheral arterial intervention is a rapidly evolving field with a significant impact on an aging population. Areas covered: Treatment concepts evolve rapidly, with new therapies providing sustainable and cost-effective solutions for complex patients. Expert opinion: Metal stenting has been replaced by the ‘leave-nothing-behind’ approach, and plain balloon angioplasty devices have been replaced by drug-coated balloons (DCBs). While paclitaxel was initially used, sirolimus has more recently shown promising outcomes. This review article provides an overview of the technology and pharmacology behind sirolimus-coated balloons (SRL-DCB) and presents existing clinical evidence of their use.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | peripheral vascular diseases,drug-coated balloons,restenosis,sirolimus,restenosis,peripheral vascular disease,drug-coated balloons,surgery,biomedical engineering ,/dk/atira/pure/subjectarea/asjc/2700/2746 |
| Faculty \ School: | Faculty of Science > School of Chemistry, Pharmacy and Pharmacology |
| UEA Research Groups: | Faculty of Science > Research Groups > Physical Chemistry and Pharmaceutics |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 28 Oct 2025 11:30 |
| Last Modified: | 19 Oct 2026 23:10 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/100813 |
| DOI: | 10.1080/17434440.2025.2574364 |
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