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ToolsSloan, Melanie, Pollak, Thomas A., D'Cruz, David, Diment, Wendy, Bosley, Michael, Lever, Elliott, Mann, Farhana, Sloan, Benjamin, Brimicombe, James, Morris, Stephen and Naughton, Felix (2025) A randomised controlled trial to assess the feasibility and acceptability of remote psychosocial and exercise interventions for people with lupus: The ADAPT feasibility trial. Rheumatology International, 45 (10). ISSN 0172-8172
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Abstract
Limited psychosocial support is available for people with lupus despite the highly reduced quality of life. This study assessed the acceptability, feasibility, and effectiveness estimations, of three (two psychosocial, one exercise) interventions. Lupus patients (N = 124) were randomised to a control arm or one of three interventions delivered remotely over 8–12 weeks: (1) listening support (The Wren project), (2) online Pilates classes, and (3) a text message and video support programme. Online follow up surveys post-intervention and six-months post-baseline included validated instruments for depression (PHQ-8), fatigue (FACIT-F), resilience (CD-RISC), acceptability measures and our co-designed “ADAPT” measure. A subsample of participants completed qualitative interviews. Hedge’s g and linear regression were used to estimate effectiveness. All interventions were feasible in terms of recruitment, time, and costs, and met the pre-defined acceptability criteria of > 75% rating the intervention as acceptable/highly acceptable. Helpfulness ratings were highest for listening support with 89% rating it as often/always helpful (62% for Pilates and 52% for Text/videos). Proportions of participants reporting that the intervention had made them feel better mentally often/always was 71% for The Wren, 57% for Pilates and 48% for the text/video group. Qualitatively, the listening support participants valued the “safe space” to talk, and several of the exercise class participants reported improvements to physical and mental health. Although the text message and video programme was acceptable, feasible, and very low cost, 41% of participants would rather have received a different intervention. Suggested text/video adaptations included greater tailoring, particularly to stage of disease journey. Attendance was low for Pilates (only 55% attended > 50% of classes). Estimates of effectiveness favoured all interventions compared to control, although most improvements reduced with time. The interventions were feasible to deliver and acceptable to patients, with indications of potential effectiveness. Further studies are needed to determine effectiveness.
| Item Type: | Article |
|---|---|
| Additional Information: | Data availability: Anonymised data will be available on reasonable request for research purposes. Funding information: This feasibility study was funded by LUPUS UK and The Lupus Trust. The funders had no role in the design, conduct or analysis of the trial, other than to advertise the trial. |
| Uncontrolled Keywords: | sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School Faculty of Medicine and Health Sciences > School of Health Sciences |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Public Health Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging Faculty of Medicine and Health Sciences > Research Groups > Behavioural and Implementation Science Faculty of Medicine and Health Sciences > Research Groups > Health Promotion |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 26 Sep 2025 13:30 |
| Last Modified: | 28 Sep 2025 23:59 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/100467 |
| DOI: | 10.1007/s00296-025-05959-4 |
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