Can AI modeling of protein structures distinguish between sensor and helper NLR immune receptors?

Toghani, AmirAli, Frijters, Raoul, Bozkurt, Tolga O., Terauchi, Ryohei, Kamoun, Sophien and Sugihara, Yu (2025) Can AI modeling of protein structures distinguish between sensor and helper NLR immune receptors? New Phytologist, 248 (1). pp. 17-23. ISSN 0028-646X

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Additional Information: The articulation of text within this manuscript was assisted by ChatGPT. Data availability: The scripts and dataset used for the phylogenetic analysis are available on GitHub (https://github.com/amiralito/Paired_NLR_AF3). The other datasets are archived on Zenodo (10.5281/zenodo.15552925). Funding information: The authors received funding from the sources listed below. The Gatsby Charitable Foundation (AT, SK, YS), Biotechnology and Biological Sciences Research Council (BBSRC) BB/P012574 (Plant Health ISP) (AT, SK, YS), BBSRC BBS/E/J/000PR9795 (Plant Health ISP – Recognition) (AT, SK, YS), BBSRC BBS/E/J/000PR9796 (Plant Health ISP – Response) (AT, SK, YS), BBSRC BBS/E/J/000PR9797 (Plant Health ISP – Susceptibility) (AT, SK, YS), BBSRC BBS/E/J/000PR9798 (Plant Health ISP – Evolution) (AT, SK, YS), BBSRC BB/X016382/1 (TOB), European Research Council (ERC) 743165 (SK), Engineering and Physical Sciences Research Council EP/Y032187/1 (SK), and Japan Society for the Promotion of Science (JSPS) 23K20042, 24H00010 (RT).
Uncontrolled Keywords: alphafold,functional specialization,nlr immune receptor,plant–pathogen interactions,protein structure,physiology,plant science ,/dk/atira/pure/subjectarea/asjc/1300/1314
Faculty \ School: Faculty of Science > The Sainsbury Laboratory
Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 06 Aug 2025 16:30
Last Modified: 01 Oct 2025 03:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/100093
DOI: 10.1111/nph.70391

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