Nutritional deficiencies following bariatric surgery: A rapid systematic review of case reports of vitamin and micronutrient deficiencies presenting more than two years post-surgery

Haughton, Sophie, Gentry, Sarah and Parretti, Helen M. (2025) Nutritional deficiencies following bariatric surgery: A rapid systematic review of case reports of vitamin and micronutrient deficiencies presenting more than two years post-surgery. Clinical Obesity. ISSN 1758-8103

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Abstract

Bariatric surgery is the most clinically- and cost-effective intervention for severe obesity. However, without adequate follow-up, it can lead to nutritional deficiencies. Patients require life-long nutritional supplements and follow-up to prevent nutritional deficiencies from developing. This rapid systematic review is the first synthesis of case reports of patients with vitamin and micronutrient deficiencies at least 2 years following bariatric surgery, the point at which patients are typically discharged from specialist bariatric services. Eighty-three cases (74 studies) met inclusion criteria. Female patients accounted for 84% of the reports. Roux-en-Y Gastric Bypass (RYGB) was the most common procedure to have been performed, followed by biliopancreatic diversion (BPD). The most frequently reported deficiencies were vitamin A (n = 15), copper (n = 14) and vitamin D (n = 23). In some cases, vitamin replacement led to symptom resolution, but some preceded permanent disability or death. Fifty-one case reports detailed factors contributing to the development of the deficiency. These could be divided into patient factors or health care factors and provide areas to target interventions, including support to adhere to supplementation, appropriate follow-up, and health professional awareness.

Item Type: Article
Additional Information: Data Availability Statement: Data sharing is not applicable to this article as no new data were created or analyzed in this study. Funding: SH received a bursary to support the completion of this work from The Sands Cox Charity, at the University of Birmingham. She received a subsequent monetary prize for a presentation delivered to the Charity and for a brief report write-up in the Charity's inhouse annual journal.
Uncontrolled Keywords: bariatric surgery,deficiency,mineral,nutrition,post-surgery,vitamin,endocrinology, diabetes and metabolism,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2712
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Centres > Public Health
Faculty of Medicine and Health Sciences > Research Centres > Mental Health and Social Care (fka Lifespan Health)
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Depositing User: LivePure Connector
Date Deposited: 05 Aug 2025 09:30
Last Modified: 06 Aug 2025 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/100053
DOI: 10.1111/cob.70035

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