Upper-rim monofunctionalisation in the synthesis of triazole- and disulfide-linked multicalix[4]- and -[6]arenes.

Gardiner, William, Camilleri, Matthew, Martinez Lozano, Luis Angel, Bew, Sean and Stephenson, G. Richard (2018) Upper-rim monofunctionalisation in the synthesis of triazole- and disulfide-linked multicalix[4]- and -[6]arenes. Chemistry - A European Journal, 24 (71). p. 144733096. ISSN 0947-6539

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    Abstract

    Covalently linked multiple calixarenes are valued in supramolecular chemistry. We report an easy and versatile synthetic route to covalently linked double and triple calix[4]arene and calix[6]arenes by a novel DMF‐controlled selective alkylation of a convenient and readily available upper‐rim dimethylaminomethyl‐substituted tetrahydroxy calix[4]arene and ‐[6]arenes. Synthetic routes to upper‐rim functionalised redox active disulfide‐linked double‐, tetra‐ and peptidohybrid‐calixarenes employing either redox chemistry (CH2SH) or thiolates (CH2S–) are also opened up from the same key starting material.

    Item Type: Article
    Faculty \ School: Faculty of Science > School of Chemistry
    Related URLs:
    Depositing User: LivePure Connector
    Date Deposited: 01 Nov 2018 13:31
    Last Modified: 09 Apr 2019 13:51
    URI: https://ueaeprints.uea.ac.uk/id/eprint/68734
    DOI: 10.1002/chem.201804755

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