Examining the relationship between autobiographical memory impairment and carer burden in dementia syndrome

Kumfor, Fiona, Teo, Drusilla, Miller, Laurie, Lah, Suncica, Mioshi, Eneida, Hodges, John R, Piguet, Olivier and Irish, Muireann (2016) Examining the relationship between autobiographical memory impairment and carer burden in dementia syndrome. Journal of Alzheimer's Disease, 51 (1). pp. 237-248. ISSN 1387-2877

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Abstract

Background: Autobiographical memory (ABM) refers to the capacity to remember one’s own past, and is known to be central for supporting one’s identity and sense of self. This capacity is commonly affected in Alzheimer’s disease (AD), as well as semantic dementia (SD) and behavioural-variant frontotemporal dementia (bvFTD). Importantly, ABM plays a critical social function, facilitating relationship intimacy and empathy, and thus loss of ABM may also negatively affect families and carers. Objective: To explore the relationship between ABM disruption and carer burden in AD, SD and bvFTD, and establish whether characteristic ABM profiles differentially relate to carer burden across dementia syndromes. Methods: We recruited 12 AD, 10 SD and 13 bvFTD patients and their primary carer. All participants completed the Autobiographical Interview to assess memory for recent and remote events. Carers completed: the Zarit Burden Interview; Depression, Anxiety and Stress Scale (DASS-21); and the Intimate Bond Measure (IBM). Results: In AD, loss of recent ABM was associated with worse psychological wellbeing of carers on the DASS-21. In contrast in SD, remote ABM dysfunction was associated with SD patients showing greater controlling behaviour within their intimate relationships. In bvFTD, surprisingly, despite pervasive ABM impairment, no relationship between extent of ABM loss and carer burden was observed. Conclusion: These preliminary results reveal that ABM impairment impacts on patients’ families and carers and suggest that these influences vary according to the pattern of ABM dysfunction. Disease-specific interventions focusing on preserved aspects of ABM may improve quality of life for both patients and carers.

Item Type:	Article
Uncontrolled Keywords:	frontotemporal dementia,alzheimer’s disease,semantic dementia,wellbeing,quality of life,relationships,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Dementia & Complexity in Later Life Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Depositing User:	Pure Connector
Date Deposited:	22 Mar 2016 09:20
Last Modified:	19 Oct 2023 01:36
URI:	https://ueaeprints.uea.ac.uk/id/eprint/57722
DOI:	10.3233/JAD-150740

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