Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics:meta-analysis

Kwok, Chun Shing, Arthur, Aaron Kobina, Anibueze, Chukwudubem Ifeanyichukwu, Singh, Sonal, Cavallazzi, Rodrigo and Loke, Yoon Kong (2012) Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics:meta-analysis. The American Journal of Gastroenterology, 107 (7). pp. 1011-9. ISSN 0002-9270

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Abstract

Several studies have raised concern regarding the possible association between proton-pump inhibitors (PPIs) and Clostridium difficile infection (CDI). We aimed to perform a systematic review of incident and recurrent CDI in PPI users, and to evaluate the relative impact of concurrent antibiotic use, or switching acid suppression to histamine-2-receptor antagonists (H2RAs).

Item Type: Article
Uncontrolled Keywords: anti-bacterial agents,clostridium difficile,enterocolitis, pseudomembranous,histamine h2 antagonists,humans,incidence,proton pump inhibitors,recurrence,risk factors
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 20 Jan 2014 16:48
Last Modified: 23 Jan 2019 13:49
URI: https://ueaeprints.uea.ac.uk/id/eprint/46600
DOI: 10.1038/ajg.2012.108

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