A novel exploratory method for visual recombination detection

Strimmer, K., Forslund, K., Holland, B. and Moulton, V. (2003) A novel exploratory method for visual recombination detection. Genome Biology, 4. R33.

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Abstract

A versatile visual approach for detecting recombination and identifying recombination breakpoints within a sequence alignment is presented. The method is based on two novel diagrams - the highway plot and the occupancy plot - that graphically portray phylogenetic inhomogeneity along an alignment, and can be viewed as a synthesis of two widely used but unrelated methods: bootscanning and quartet-mapping. To illustrate the method, simulated data and HIV-1 and influenza A datasets are investigated.

Item Type: Article
Faculty \ School: Faculty of Science > School of Computing Sciences
Related URLs:
Depositing User: Vishal Gautam
Date Deposited: 13 Jun 2011 13:38
Last Modified: 13 Dec 2018 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/21685
DOI: 10.1186/gb-2003-4-5-r33

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