Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites

Wang, X, Jobe, M, Tyler, KM and Steverding, D (2008) Efficacy of common laboratory disinfectants and heat on killing trypanosomatid parasites. Parasites & Vectors, 1. ISSN 1756-3305

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    Abstract

    The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach (0.05% NaOCl) killed all three trypanosomatids. Ethanol and water destroyed the parasites within 5 min at concentrations of 15-17.5% and 80-90%, respectively. All three organisms were also killed when treated for 5 min at 50 degrees C. The results indicate that the disinfectants, water and temperature treatment (i.e. autoclaving) are suitable laboratory hygiene measures against trypanosomatid parasites.

    Item Type: Article
    Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
    Related URLs:
    Depositing User: EPrints Services
    Date Deposited: 25 Nov 2010 11:13
    Last Modified: 11 Apr 2019 15:35
    URI: https://ueaeprints.uea.ac.uk/id/eprint/14998
    DOI: 10.1186/1756-3305-1-35

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