Items where Research Group is "Molecular and Tissue Pharmacology

Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, O'Connell, Maria Anne ORCID: https://orcid.org/0000-0002-0267-0951 and Howell, Lesley Ann (2017) Peptide-directed binding for the discovery of modulators of α-helix-mediated protein-protein interactions: Proof-of-concept studies with the apoptosis regulator Mcl-1. Angewandte Chemie-International Edition, 56 (35). 10446–10450. ISSN 1433-7851

Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Cominetti, Marco M. D., Waller, Zoe A. E., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Bochmann, Manfred ORCID: https://orcid.org/0000-0001-7736-5428 (2017) Cytotoxicity of pyrazine-based cyclometalated (C^Npz^C)Au(III) carbene complexes: Impact of the nature of the ancillary ligand on the biological properties. Inorganic Chemistry, 56 (10). 5728–5740. ISSN 0020-1669

Bertrand, Benoît, Romanov, Alexander S, Brooks, Mark, Schmidt, Claudia, Ott, Ingo, O'Connell, Maria Anne ORCID: https://orcid.org/0000-0002-0267-0951 and Bochmann, Manfred ORCID: https://orcid.org/0000-0001-7736-5428 (2017) Synthesis, structure and cytotoxicity of cyclic (alkyl)(amino) carbene and acyclic carbene complexes of group 11 metals. Dalton Transactions, 46. pp. 15875-15887. ISSN 1477-9226

Bulman Page, Philip C., Goodyear, Ross L., Horton, Alexandra E., Chan, Yohan, Karim, Rehana, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Hamilton, Christopher, Slawin, Alexandra M. Z., Buckley, Benjamin R. and Allin, Steven M. (2017) Formal total synthesis of (+)-C9-deoxyomuralide from l-leucine using a double sacrificial chirality transfer approach. The Journal of Organic Chemistry, 82 (23). 12209–12223. ISSN 0022-3263

De Luca, Simone N., Ziko, Ilvana, Dhuna, Kshitija, Sominsky, Luba, Tolcos, Mary, Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781 and Spencer, Sarah J. (2017) Neonatal overfeeding by small-litter rearing sensitises hippocampal microglial responses to immune challenge: Reversal with neonatal repeated injections of saline or minocycline. Journal of Neuroendocrinology, 29 (11). ISSN 0953-8194

De Santis, Stefania, Galleggiante, Vanessa, Scandiffio, Letizia, Liso, Marina, Sommella, Eduardo, Sobolewski, Anastasia, Spilotro, Vito, Pinto, Aldo, Campiglia, Pietro, Serino, Grazia, Santino, Angelo, Notarnicola, Maria and Chieppa, Marcello (2017) Secretory leukoprotease inhibitor (Slpi) expression is required for educating murine dendritic cells inflammatory response following quercetin exposure. Nutrients, 9 (7). ISSN 2072-6643

Jeffery, Victoria, Goldson, Andrew J., Dainty, Jack R. ORCID: https://orcid.org/0000-0002-0056-1233, Chieppa, Marcello and Sobolewski, Anastasia (2017) IL-6 signaling regulates small intestinal crypt homeostasis. Journal of Immunology, 199 (1). pp. 304-311. ISSN 0022-1767

Kokkinopoulos, Ioannis, Wong, Mei Mei, Potter, Claire M. F., Xie, Yao, Yu, Baoqi, Warren, Derek T., Nowak, Witold N., Le Bras, Alexandra, Ni, Zhichao, Zhou, Chao, Ruan, Xiongzhong, Karamariti, Eirini, Hu, Yanhua, Zhang, Li and Xu, Qingbo (2017) Adventitial SCA-1+ progenitor cell gene sequencing reveals the mechanisms of cell migration in response to hyperlipidemia. Stem Cell Reports, 9 (2). 681–696.

Reed, James, Stephenson, Michael J ORCID: https://orcid.org/0000-0002-2594-1806, Miettinen, Karel, Brouwer, Bastiaan, Leveau, Aymeric, Brett, Paul, Goss, Rebecca J M, Goossens, Alain, O'Connell, Maria A ORCID: https://orcid.org/0000-0002-0267-0951 and Osbourn, Anne (2017) A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules. Metabolic Engineering, 42. 185–193. ISSN 1096-7176

Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Layhadi, Janice A., Bibic, Lucka, Dhuna, Kshitija and Fountain, Samuel J. ORCID: https://orcid.org/0000-0002-6028-0548 (2017) P2X4 receptor function in the nervous system and current breakthroughs in pharmacology. Frontiers in Pharmacology, 8. ISSN 1663-9812

Warner, Emily F., Smith, Michael J., Zhang, Qingzhi, Raheem, K. Saki, O'Hagan, David, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Kay, Colin D. (2017) Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells. Molecular Nutrition & Food Research, 61 (9). ISSN 1613-4125

Wilkinson, Shane M, Barron, Melissa L, O'Brien-Brown, James, Janssen, Bieneke, Stokes, Leanne ORCID: https://orcid.org/0000-0003-4013-6781, Werry, Eryn L., Chishty, Mansoor, Skarratt, Kristen K., Ong, Jennifer A., Hibbs, David E., Vugts, Danielle J., Fuller, Stephen, Windhorst, Albert D. and Kassiou, Michael (2017) Pharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonist. ACS Chemical Neuroscience, 8 (11). 2374–2380. ISSN 1948-7193

Williams, Morwen, Green, Adam I, Fernandez-Cestau, Julio, Hughes, David L, O'Connell, Maria Anne ORCID: https://orcid.org/0000-0002-0267-0951, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Bertrand, Benoit and Bochmann, Manfred ORCID: https://orcid.org/0000-0001-7736-5428 (2017) (C^Npz^C)AuIII complexes of acyclic carbene ligands: synthesis and anticancer properties. Dalton Transactions, 46 (39). 13397–13408. ISSN 1477-9226

Zhou, Can, Li, Chen, Zhou, Bin, Sun, Huaqin, Koullourou, Victoria, Holt, Ian, Puckelwartz, Megan J, Warren, Derek T, Hayward, Robert, Lin, Ziyuan, Zhang, Lin, Morris, Glenn E, McNally, Elizabeth M, Shackleton, Sue, Rao, Li, Shanahan, Catherine M and Zhang, Qiuping (2017) Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis. Human Molecular Genetics, 26 (12). pp. 2258-2276. ISSN 0964-6906