Items where Research Group is "Chemical Biology and Medicinal Chemistry (former - to 2021)

Article

Beekman, Andrew Michael ORCID: https://orcid.org/0000-0002-3056-6406, O'Connell, Maria Anne ORCID: https://orcid.org/0000-0002-0267-0951 and Howell, Lesley Ann (2017) Peptide-directed binding for the discovery of modulators of α-helix-mediated protein-protein interactions: Proof-of-concept studies with the apoptosis regulator Mcl-1. Angewandte Chemie-International Edition, 56 (35). 10446–10450. ISSN 1433-7851

Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus ORCID: https://orcid.org/0000-0001-7250-5639, Cominetti, Marco M. D., Waller, Zoe A. E., Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951 and Bochmann, Manfred ORCID: https://orcid.org/0000-0001-7736-5428 (2017) Cytotoxicity of pyrazine-based cyclometalated (C^Npz^C)Au(III) carbene complexes: Impact of the nature of the ancillary ligand on the biological properties. Inorganic Chemistry, 56 (10). 5728–5740. ISSN 0020-1669

Borrello, Maria Teresa, Schinor, Benjamin, Bartels, Katharina, Benelkebir, Hanae, Pereira, Sara, Al-Jamal, Wafa T., Douglas, Leon, Duriez, Patrick J., Packham, Graham, Haufe, Günter and Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999 (2017) Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A). Bioorganic & Medicinal Chemistry Letters, 27 (10). 2099–2101. ISSN 0960-894X

Bulman Page, Philip C., Goodyear, Ross L., Horton, Alexandra E., Chan, Yohan, Karim, Rehana, O'Connell, Maria A. ORCID: https://orcid.org/0000-0002-0267-0951, Hamilton, Christopher, Slawin, Alexandra M. Z., Buckley, Benjamin R. and Allin, Steven M. (2017) Formal total synthesis of (+)-C9-deoxyomuralide from l-leucine using a double sacrificial chirality transfer approach. The Journal of Organic Chemistry, 82 (23). 12209–12223. ISSN 0022-3263

Conforti, Franco, Davies, Elizabeth R., Calderwood, Claire J., Thatcher, Thomas H., Jones, Mark G., Smart, David E., Mahajan, Sumeet, Alzetani, Aiman, Havelock, Tom, Maher, Toby M., Molyneaux, Philip L., Thorley, Andrew J., Tetley, Teresa D., Warner, Jane A.­, Packham, Graham, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Skipp, Paul J., Marshall, Benjamin J., Richeldi, Luca, Sime, Patricia J., O’reilly, Katherine M.a. and Davies, Donna E. (2017) The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis. Oncotarget, 8. pp. 48737-48754. ISSN 1949-2553

Hau, Mirjam, Zenk, Fides, Ganesan, A. ORCID: https://orcid.org/0000-0003-4862-7999, Iovino, Nicola and Jung, Manfred (2017) Cellular analysis of the action of epigenetics drugs and probes. Epigenetics, 12 (5). pp. 308-322. ISSN 1559-2294

Loi, Vu Van, Harms, Manuela, Müller, Marret, Huyen, Nguyen Thi Thu, Hamilton, Christopher J., Hochgräfe, Falko, Pane-Farre, Jan and Antelmann, Haike (2017) Real-time imaging of the bacillithiol redox potential in the human pathogen Staphylococcus aureus using a genetically encoded bacilliredoxin-fused redox biosensor. Antioxidants & Redox Signaling, 26 (15). pp. 835-848. ISSN 1523-0864

Oosthuizen, Carel, Arbach, Miriam, Meyer, Debra, Hamilton, Chris and Lall, Namrita (2017) Diallyl polysulfides from Allium sativum as immunomodulators, hepatoprotectors, and antimycobacterial agents. Journal of Medicinal Food, 20 (7). pp. 685-690. ISSN 1096-620X

Sheng, Qiran, Neaverson, Joseph C., Mahmoud, Tasnim, Stevenson, Clare E. M., Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 and Waller, Zoë A. E. (2017) Identification of new DNA i-motif binding ligands through a fluorescent intercalator displacement assay. Organic & Biomolecular Chemistry, 15 (27). pp. 5669-5673. ISSN 1477-0520

Threadgill, Michael D., Matthews, Susan E. ORCID: https://orcid.org/0000-0001-8821-0851 and Giuntini, Francesca (2017) 25th Conference of GP2A. Pharmaceuticals, 10 (4). ISSN 1424-8247

Williams, Morwen, Green, Adam I, Fernandez-Cestau, Julio, Hughes, David L, O'Connell, Maria Anne ORCID: https://orcid.org/0000-0002-0267-0951, Searcey, Mark ORCID: https://orcid.org/0000-0003-2273-8949, Bertrand, Benoit and Bochmann, Manfred ORCID: https://orcid.org/0000-0001-7736-5428 (2017) (C^Npz^C)AuIII complexes of acyclic carbene ligands: synthesis and anticancer properties. Dalton Transactions, 46 (39). 13397–13408. ISSN 1477-9226

Wright, Elisé P, Huppert, Julian L and Waller, Zoë A E (2017) Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH. Nucleic Acids Research, 2017 (1). ISSN 0305-1048

Wright, Elisé P., Lamparska, Katarzyna, Smith, Steven S. and Waller, Zoë A. E. (2017) Substitution of cytosine with guanylurea decreases the stability of i-motif DNA. Biochemistry, 56 (36). pp. 4879-4883. ISSN 0006-2960