Items where School is "University of East Anglia > Faculty of Medicine and Health Sciences > Research Groups > Prostate Cancer Studies

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Attard, Gerhardt, Cooper, Colin S and de Bono, Johann S (2009) Steroid hormone receptors in prostate cancer:a hard habit to break? Cancer Cell, 16 (6). pp. 458-62. ISSN 1878-3686

Attard, Gerhardt, Reid, Alison H M, Yap, Timothy A, Raynaud, Florence, Dowsett, Mitch, Settatree, Sarah, Barrett, Mary, Parker, Christopher, Martins, Vanessa, Folkerd, Elizabeth, Clark, Jeremy, Cooper, Colin S, Kaye, Stan B, Dearnaley, David, Lee, Gloria and de Bono, Johann S (2008) Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Journal of Clinical Oncology, 26 (28). pp. 4563-71. ISSN 1527-7755

Attard, Gerhardt, Rizzo, Sian, Ledaki, Ioanna, Clark, Jeremy, Reid, Alison H M, Thompson, Alan, Khoo, Vincent, de Bono, Johann S, Cooper, Colin S and Hudson, David L (2009) A novel, spontaneously immortalized, human prostate cancer cell line, Bob, offers a unique model for pre-clinical prostate cancer studies. The Prostate, 69 (14). pp. 1507-20. ISSN 1097-0045

Attard, Gerhardt, Swennenhuis, Joost F, Olmos, David, Reid, Alison H M, Vickers, Elaine, A'Hern, Roger, Levink, Rianne, Coumans, Frank, Moreira, Joana, Riisnaes, Ruth, Oommen, Nikhil Babu, Hawche, George, Jameson, Charles, Thompson, Emilda, Sipkema, Ronald, Carden, Craig P, Parker, Christopher, Dearnaley, David, Kaye, Stan B, Cooper, Colin S, Molina, Arturo, Cox, Michael E, Terstappen, Leon W M M and de Bono, Johann S (2009) Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Research, 69 (7). pp. 2912-8. ISSN 0008-5472

Attard, Gerhardt, de Bono, Johann S, Clark, Jeremy and Cooper, Colin S (2010) Studies of TMPRSS2-ERG gene fusions in diagnostic trans-rectal prostate biopsies. Clinical Cancer Research, 16 (4). 1340; author reply 1340. ISSN 1078-0432


Battaglia, Sebastiano, Maguire, Orla, Thorne, James L, Hornung, Laura B, Doig, Craig L, Liu, Song, Sucheston, Lara E, Bianchi, Anna, Khanim, Farhat L, Gommersall, Lyndon M, Coulter, Henry S O, Rakha, Serena, Giddings, Ian, O'Neill, Laura P, Cooper, Colin S, McCabe, Christopher J, Bunce, Christopher M and Campbell, Moray J (2010) Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion. Carcinogenesis, 31 (9). pp. 1650-60. ISSN 0143-3334

Bowles, Kristian M, Bloxham, David M, Perry, David J and Baglin, Trevor P (2006) Discrepancy between impedance and immunofluorescence platelet counting has implications for clinical decision making in patients with idiopathic thrombocytopenia purpura. British Journal of Haematology, 134 (3). pp. 320-2. ISSN 0007-1048

Bowles, Kristian M, Vallier, Ludovic, Smith, Joseph R, Alexander, Morgan R J and Pedersen, Roger A (2006) HOXB4 overexpression promotes hematopoietic development by human embryonic stem cells. Stem Cells, 24 (5). pp. 1359-1369. ISSN 1066-5099

Bowles, Kristian M, Warner, Brian A and Baglin, Trevor P (2006) Platelet mass has prognostic value in patients with myelodysplastic syndromes. British Journal of Haematology, 135 (2). pp. 198-200. ISSN 0007-1048

Brewer, Daniel, Santarius, T, Shipley, J, Stratton, MR and Cooper, CS (2010) A census of amplified and overexpressed human cancer genes. Nature Reviews, 10 (1). pp. 59-64.


Clark, Jeremy, Edwards, Sandra, Feber, Andrew, Flohr, Penny, John, Megan, Giddings, Ian, Crossland, Sue, Stratton, Michael R, Wooster, Richard, Campbell, Colin and Cooper, Colin S (2003) Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays. Oncogene, 22 (8). pp. 1247-52. ISSN 0950-9232

Clark, Jeremy, Edwards, Sandra, John, Megan, Flohr, Penny, Gordon, Tony, Maillard, Karine, Giddings, Ian, Brown, Carolanne, Bagherzadeh, Azadeh, Campbell, Colin, Shipley, Janet, Wooster, Richard and Cooper, Colin S (2002) Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones. Genes, Chromosomes & Cancer, 34 (1). pp. 104-14. ISSN 1045-2257

Clark, Jeremy P and Cooper, Colin S (2009) ETS gene fusions in prostate cancer. Nature Reviews Urology, 6 (8). pp. 429-39. ISSN 1759-4820

Cooper, Colin (2008) Editorial comment on:ADAM9 expression is a significant and independent prognostic marker of PSA relapse in prostate cancer. European Urology, 54 (5). pp. 1107-8. ISSN 0302-2838

Cooper, Colin A, Mulder, David T, Allison, Sarah E, Pilar, Ana Victoria C and Coombes, Brian K (2013) The SseC translocon component in Salmonella enterica serovar Typhimurium is chaperoned by SscA. BMC Microbiology, 13.

Cooper, Colin A, Walsh, Logan A and Damjanovski, Sashko (2007) Peroxisome biogenesis occurs in late dorsal-anterior structures in the development of Xenopus laevis. Developmental Dynamics, 236 (12). pp. 3554-61. ISSN 1058-8388

Cooper, Colin A, Zhang, Kun, Andres, Sara N, Fang, Yuan, Kaniuk, Natalia A, Hannemann, Mandy, Brumell, John H, Foster, Leonard J, Junop, Murray S and Coombes, Brian K (2010) Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host. PLoS Pathogens, 6 (2). ISSN 1553-7366

Cooper, Colin S (2002) Smoking, lung cancers and their TP53 mutations. Mutagenesis, 17 (4). pp. 279-80. ISSN 0267-8357

Cooper, Colin S, Nicholson, Andrew G, Foster, Christopher, Dodson, Andrew, Edwards, Sandra, Fletcher, Anne, Roe, Toby, Clark, Jeremy, Joshi, Anupam, Norman, Andrew, Feber, Andrew, Lin, Dongmei, Gao, Yanning, Shipley, Janet and Cheng, Shu-Jun (2006) Nuclear overexpression of the E2F3 transcription factor in human lung cancer. Lung Cancer, 54 (2). pp. 155-62. ISSN 0169-5002


Feber, Andrew, Clark, Jeremy, Goodwin, Graham, Dodson, Andrew R, Smith, Paul H, Fletcher, Anne, Edwards, Sandra, Flohr, Penny, Falconer, Alison, Roe, Toby, Kovacs, Gyula, Dennis, Nening, Fisher, Cyril, Wooster, Richard, Huddart, Robert, Foster, Christopher S and Cooper, Colin S (2004) Amplification and overexpression of E2F3 in human bladder cancer. Oncogene, 23 (8). pp. 1627-30. ISSN 0950-9232

Foster, Christopher S and Cooper, Colin S (2009) Urgent need to develop independent biomarkers for functional, diagnostic and prognostic application in oncology research. Biomarkers in Medicine, 3 (4). pp. 329-33. ISSN 1752-0371


Gibbs, Simon D J, Williams, Stuart M, Tyler, Xenia, Pearson, John, Bennie, Mary Jane and Bowles, Kristian M (2011) You can't have your cake and eat it too. Gut, 60 (6). 852, 860. ISSN 0017-5749


Heasman, Sally-Anne, Zaitseva, Lyubov, Bowles, Kristian M, Rushworth, Stuart A and Macewan, David J (2011) Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1. Oncotarget, 2 (9). pp. 658-668.


Jiang, Jia-Qian, Cooper, Colin and Ouki, Sabeha (2002) Comparison of modified montmorillonite adsorbents. Part I:Preparation, characterization and phenol adsorption. Chemosphere, 47 (7). pp. 711-6. ISSN 0045-6535

Ju, Young Seok, Tubio, Jose M.c., Mifsud, William, Fu, Beiyuan, Davies, Helen R., Ramakrishna, Manasa, Li, Yilong, Yates, Lucy, Gundem, Gunes, Tarpey, Patrick S., Behjati, Sam, Papaemmanuil, Elli, Martin, Sancha, Fullam, Anthony, Gerstung, Moritz, Nangalia, Jyoti, Green, Anthony R., Caldas, Carlos, Borg, Åke, Tutt, Andrew, Lee, Ming Ta Michael, Van't Veer, Laura J., Tan, Benita K.t., Aparicio, Samuel, Span, Paul N., Martens, John W.M., Knappskog, Stian, Vincent-Salomon, Anne, Børresen-Dale, Anne-Lise, Eyfjörd, Jórunn Erla, Flanagan, Adrienne M., Foster, Christopher, Neal, David E., Cooper, Colin, Eeles, Rosalind, Lakhani, Sunil R., Desmedt, Christine, Thomas, Gilles, Richardson, Andrea L., Purdie, Colin A., Thompson, Alastair M., Mcdermott, Ultan, Yang, Fengtang, Nik-zainal, Serena, Campbell, Peter J. and Stratton, Michael R. (2015) Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Research, 25 (6). pp. 814-824. ISSN 1088-9051


Kudahetti, Sak, Fisher, Gabrielle, Ambroisine, Laurence, Foster, Christopher, Reuter, Victor, Eastham, James, Møller, Henrik, Kattan, Michael W, Cooper, Colin S, Scardino, Peter, Cuzick, Jack and Berney, Daniel M (2009) p53 immunochemistry is an independent prognostic marker for outcome in conservatively treated prostate cancer. BJU International, 104 (1). pp. 20-4. ISSN 1464-4096

Kudahetti, Sakunthala C, Fisher, Gabrielle, Ambroisine, Laurence, Prowse, David, Kattan, Michael W, Foster, Christopher S, Møller, Henrik, Oliver, Tim, Fletcher, Anne, Cooper, Colin, Reuter, Victor, Scardino, Peter, Cuzick, Jack, Berney, Daniel M and , Transatlantic Prostate Group (2010) Immunohistochemistry for p16, but not Rb or p21, is an independent predictor of prognosis in conservatively treated, clinically localised prostate cancer. Plant Pathology, 42 (6). pp. 519-23. ISSN 0032-0862


Ladanyi, Marc, Antonescu, Cristina R, Leung, Denis H, Woodruff, James M, Kawai, Akira, Healey, John H, Brennan, Murray F, Bridge, Julia A, Neff, James R, Barr, Frederic G, Goldsmith, Jeffrey D, Brooks, John S J, Goldblum, John R, Ali, Syed Z, Shipley, Janet, Cooper, Colin S, Fisher, Cyril, Skytting, Björn and Larsson, Olle (2002) Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma:a multi-institutional retrospective study of 243 patients. Cancer Research, 62 (1). pp. 135-40. ISSN 0008-5472

Lee, Yin-Fai, John, Megan, Falconer, Alison, Edwards, Sandra, Clark, Jeremy, Flohr, Penny, Roe, Toby, Wang, Rubin, Shipley, Janet, Grimer, Robert J, Mangham, D Chas, Thomas, J Meirion, Fisher, Cyril, Judson, Ian and Cooper, Colin S (2004) A gene expression signature associated with metastatic outcome in human leiomyosarcomas. Cancer Research, 64 (20). pp. 7201-4. ISSN 0008-5472


Macewan, David, Bowles, Kristian and Rushworth, Stuart (2013) Emerging therapy targeting tyrosine-protein kinase BTK: potential for ibrutinib and other BTK inhibitors. Drugs of the Future, 38 (8). p. 569. ISSN 2013-0368

McIntyre, Alan, Summersgill, Brenda, Grygalewicz, Beata, Gillis, Ad J M, Stoop, J, van Gurp, Ruud J H L M, Dennis, Nening, Fisher, Cyril, Huddart, Robert, Cooper, Colin, Clark, Jeremy, Oosterhuis, J Wolter, Looijenga, Leendert H J and Shipley, Janet (2005) Amplification and overexpression of the KIT gene is associated with progression in the seminoma subtype of testicular germ cell tumors of adolescents and adults. Cancer Research, 65 (18). pp. 8085-9. ISSN 0008-5472

McIntyre, Alan, Summersgill, Brenda, Jafer, Osman, Rodriguez, Sandrine, Zafarana, Gaetano, Oosterhuis, J Wolter, Gillis, Ad Jm, Looijenga, Leendert, Cooper, Colin, Huddart, Robert, Clark, Jeremy and Shipley, Janet (2004) Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones. Oncogene, 23 (56). pp. 9142-7. ISSN 0950-9232

Mitra, Anita, Jameson, Charles, Barbachano, Yolanda, Sanchez, Lydia, Kote-Jarai, Zsofia, Peock, Susan, Sodha, Nayanta, Bancroft, Elizabeth, Fletcher, Anne, Cooper, Colin, Easton, Douglas, Eeles, Rosalind, Foster, Christopher S and , IMPACT Steering Committee and IMPACT and EMBRACE Collaborators (2009) Overexpression of RAD51 occurs in aggressive prostatic cancer. Histopathology, 55 (6). pp. 696-704. ISSN 1365-2559

Mourtada-Maarabouni, Mirna, Keen, Jennifer, Clark, Jeremy, Cooper, Colin S and Williams, Gwyn T (2006) Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes. Experimental Cell Research, 312 (10). pp. 1745-52. ISSN 0014-4827

Mulder, David T, Cooper, Colin A and Coombes, Brian K (2012) Type VI secretion system-associated gene clusters contribute to pathogenesis of Salmonella enterica serovar Typhimurium. Infection and Immunity, 80 (6). pp. 1996-2007. ISSN 0019-9567

Murray, Megan, Auger, Martin and Bowles, Kristian (2014) Overcoming bortezomib resistance in multiple myeloma. Biochemical Society Transactions, 42 (4). pp. 804-808. ISSN 0300-5127

Murray, Megan Y, Rushworth, Stuart A, Zaitseva, Lyubov, Bowles, Kristian M and Macewan, David J (2013) Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. Cell Cycle, 12 (13). pp. 2144-2153. ISSN 1551-4005


Nimmagadda, S C, Frey, S, Edelmann, B, Hellmich, C, Zaitseva, L, König, G M, Kostenis, E, Bowles, K M and Fischer, T (2018) Bruton’s tyrosine kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia. Leukemia, 32. 846–849. ISSN 0887-6924


Olsson, A Yvonne and Cooper, Colin S (2005) The molecular basis of prostate cancer. British Journal of Hospital Medicine, 66 (11). pp. 612-6. ISSN 1750-8460


Perani, Michela, Antonson, Per, Hamoudi, Rifat, Ingram, Catherine J E, Cooper, Colin S, Garrett, Michelle D and Goodwin, Graham H (2005) The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins. Journal of Biological Chemistry, 280 (52). pp. 42863-76. ISSN 0021-9258

Perani, Michela, Ingram, Catherine J E, Cooper, Colin S, Garrett, Michelle D and Goodwin, Graham H (2003) Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers. Oncogene, 22 (50). pp. 8156-67. ISSN 0950-9232

Pickard, Mark R, Edwards, Sandra E, Cooper, Colin S and Williams, Gwyn T (2010) Apoptosis regulators Fau and Bcl-G are down-regulated in prostate cancer. The Prostate, 70 (14). pp. 1513-23. ISSN 1097-0045

Piddock, Rachel E., Marlein, Christopher R., Abdul-Aziz, Amina, Shafat, Manar S., Auger, Martin J., Bowles, Kristian M. and Rushworth, Stuart A. (2018) Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC. Journal of Hematology & Oncology, 11. ISSN 1756-8722

Pilar, Ana Victoria C, Reid-Yu, Sarah A, Cooper, Colin A, Mulder, David T and Coombes, Brian K (2013) Active modification of host inflammation by Salmonella. Gut Microbes, 4 (2). pp. 140-5. ISSN 1949-0976

Pilar, Ana Victoria C, Reid-Yu, Sarah A, Cooper, Colin A, Mulder, David T and Coombes, Brian K (2012) GogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1. PLoS Pathogens, 8 (6). ISSN 1553-7366

Pozo, Anna L, Godfrey, Edmund M and Bowles, Kristian M (2009) Splenomegaly:investigation, diagnosis and management. Blood Reviews, 23 (3). pp. 105-11. ISSN 1532-1681


Ren, Guoping, Liu, Xiaoyan, Mao, Xueying, Zhang, Yanling, Stankiewicz, Elzbieta, Hylands, Lucy, Song, Rongrong, Berney, Daniel M, Clark, Jeremy, Cooper, Colin and Lu, Yong-Jie (2012) Identification of frequent BRAF copy number gain and alterations of RAF genes in Chinese prostate cancer. Genes, Chromosomes & Cancer, 51 (11). pp. 1014-23. ISSN 1045-2257

Rigau, Marina, Olivan, Mireia, Garcia, Marta, Sequeiros, Tamara, Montes, Melania, Colás, Eva, Llauradó, Marta, Planas, Jacques, Torres, Inés de, Morote, Juan, Cooper, Colin, Reventós, Jaume, Clark, Jeremy and Doll, Andreas (2013) The present and future of prostate cancer urine biomarkers. International Journal of Molecular Sciences, 14 (6). pp. 12620-49. ISSN 1422-0067

Rushworth, S, Bowles, KM, Barrera Briceno, LN, Murray, MY, Zaitseva, L and Macewan, DJ (2013) BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB. Cellular Signalling, 25 (1). pp. 106-112.

Rushworth, SA, Bowles, KM and Macewan, DJ (2011) High Basal Nuclear Levels of Nrf2 in Acute Myeloid Leukemia Reduces Sensitivity to Proteasome Inhibitors. Cancer Research, 71 (5). pp. 1999-2009. ISSN 0008-5472

Rushworth, SA, Zaitseva, L, Langa Marcano, S, Bowles, KM and Macewan, DJ (2010) FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism. Oncotarget, 1 (5). pp. 359-366. ISSN 1949-2553

Rushworth, SA, Zaitseva, L, Murray, MY, Shah, NM, Bowles, KM and Macewan, DJ (2012) The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance. Blood, 120 (26). pp. 5188-5198. ISSN 0006-4971

Rushworth, Stuart, Macewan, David and Bowles, Kristian (2013) Ibrutinib in relapsed chronic lymphocytic leukemia. New England Journal of Medicine, 369 (13). pp. 1277-8. ISSN 1533-4406

Rushworth, Stuart A, Bowles, Kristian M, Raninga, Prahlad and MacEwan, David J (2010) NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction. Cancer Research, 70 (7). pp. 2973-2983. ISSN 0008-5472


Seguna, Ryan, Maw, Kyaw Z, Lyall, Hamish D and Bowles, Kristian M (2014) “Haemorrhagic disease of the newborn” 89 years later than expected: vitamin K deficiency bleeding. The Lancet, 384 (9942). p. 556. ISSN 0140-6736

Shah, N M, Zaitseva, L, Bowles, K M, Macewan, D J and Rushworth, S A (2015) NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival. Cell Death and Differentiation, 22. pp. 654-664. ISSN 1350-9047

Shah, Niraj, Rushworth, Stuart, Murray, Megan, Bowles, Kristian and Macewan, David (2013) Understanding the role of NRF2-regulated miRNAs in human malignancies. Oncotarget, 4 (8). pp. 1130-1142. ISSN 1949-2553


Taylor, Anna L, Bowles, Kristian M, Callaghan, Christopher J, Wimperis, Jenny Z, Grant, John W, Marcus, Robert E and Bradley, J Andrew (2006) Anthracycline-based chemotherapy as first-line treatment in adults with malignant posttransplant lymphoproliferative disorder after solid organ transplantation. Transplantation, 82 (3). pp. 375-81. ISSN 0041-1337

Thomsen, Martin K, Ambroisine, Laurence, Wynn, Sarah, Cheah, Kathryn S E, Foster, Christopher S, Fisher, Gabrielle, Berney, Daniel M, Møller, Henrik, Reuter, Victor E, Scardino, Peter, Cuzick, Jack, Ragavan, Narasimhan, Singh, Paras B, Martin, Francis L, Butler, Christopher M, Cooper, Colin S, Swain, Amanda and , Transatlantic Prostate Group (2010) SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Research, 70 (3). pp. 979-87. ISSN 0008-5472

Tomljenovic-Berube, Ana M, Henriksbo, Brandyn, Porwollik, Steffen, Cooper, Colin A, Tuinema, Brian R, McClelland, Michael and Coombes, Brian K (2013) Mapping and regulation of genes within Salmonella pathogenicity island 12 that contribute to in vivo fitness of Salmonella enterica Serovar Typhimurium. Infection and Immunity, 81 (7). pp. 2394-404. ISSN 0019-9567


Walsh, Logan A, Cooper, Colin A and Damjanovski, Sashko (2007) Soluble membrane-type 3 matrix metalloprioteinase causes changes in gene expression and increased gelatinase activity during Xenopus laevis development. International Journal of Developmental Biology, 51 (5). pp. 389-95. ISSN 0214-6282


Zaitseva, Lyubov, Murray, Megan Y, Shafat, Manar S., Lawes, Matthew J, MacEwan, David J, Bowles, Kristian M and Rushworth, Stuart A (2014) Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML. Oncotarget, 5 (20). pp. 9930-9938. ISSN 1949-2553

This list was generated on Thu Jul 18 16:30:01 2019 BST.