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Number of items at this level: 77.

A

Ahire, Jayshree H., Chambrier, Isabelle, Mueller, Anja, Bao, Yongping and Chao, Yimin (2013) Synthesis of D-Mannose Capped Silicon Nanoparticles and Their Interactions with MCF-7 Human Breast Cancerous Cells. ACS Applied Materials & Interfaces, 5 (15). pp. 7384-7391. ISSN 1944-8244

Armbruester, V., Sauter, M., Roemer, K., Best, B., Hahn, S., Nty, A., Schmid, A., Philipp, S., Mueller, A. and Mueller-Lantzsch, N. (2004) Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X. Journal of Virology, 78 (19). pp. 10310-10319. ISSN 0022-538X

Atkinson, S. H., Rockett, K., Sirugo, G., Bejon, P. A., Fulford, A., O'Connell, M. A., Bailey, R., Kwiatkowski, D. P. and Prentice, A. M. (2006) Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype. PLoS Medicine, 3 (5). ISSN 1549-1277

Atkinson, S. H., Rockett, K. A., Morgan, G., Bejon, P. A., Sirugo, G., O'Connell, Maria, Hanchard, N., Kwiatkowski, D. P. and Prentice, A. M. (2008) Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Blood, 112 (10). pp. 4276-4283. ISSN 0006-4971

B

Beekman, Andrew Michael, O'Connell, Maria Anne and Howell, Lesley Ann (2017) Peptide-Directed Binding for the Discovery of Modulators of α-Helix-Mediated Protein-Protein Interactions: Proof-of-Concept Studies with the Apoptosis Regulator Mcl-1. Angewandte Chemie International Edition, 56 (35). 10446–10450. ISSN 1433-7851

Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus, Cominetti, Marco M.D., Waller, Zoe A.E., Searcey, Mark, O'Connell, Maria A. and Bochmann, Manfred (2017) Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties. Inorganic Chemistry, 56 (10). 5728–5740. ISSN 0020-1669

Biesalski, H. K., Brummer, R. J., Konig, J., O'Connell, M. A., Ovesen, L., Rechkemmer, G., Stos, K. and Thurnham, D. I. (2003) Micronutrient deficiencies - Hohenheim Consensus Conference. European Journal of Nutrition, 42 (6). pp. 353-363. ISSN 1436-6207

Bombelli, Francesca Baldelli, Webster, Carl A, Moncrieff, Marc and Sherwood, Victoria (2014) The scope of nanoparticle therapies for future metastatic melanoma treatment. The Lancet Oncology, 15 (1). e22-e32. ISSN 1470-2045

Brown, K, Yang, P, Salvador, D, Kulikauskas, R, Ruohola-Baker, H, Robitaille, A M, Chien, A J, Moon, R T and Sherwood, V (2017) WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner. Oncogene, 36. 3119–3136. ISSN 0950-9232

C

Cardaba, Clara Moyano, Kerr, Jason S. and Mueller, Anja (2008) CCR5 internalisation and signalling have different dependence on membrane lipid raft integrity. Cellular Signalling, 20 (9). pp. 1687-1694.

Cardaba, Clara Moyano and Mueller, Anja (2009) Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells. Biochemical Pharmacology, 78 (8). pp. 974-982.

Chalmers, A. D., Lacham, K., Shin, Y., Sherwood, V., Cho, K. W. Y. and Papalopulu, N. (2006) Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis. Mechanisms of Development, 123 (9). pp. 702-718. ISSN 0925-4773

Collison, DJ, Tovell, VE, Coombes, L.J., Duncan, G and Sanderson, J (2005) Potentiation of ATP-induced Ca(2+) mobilisation in human retinal pigment epithelial cells. Experimental Eye Research, 80 (4). pp. 465-475. ISSN 1096-0007

Cornish, K.C., Sanderson, J and Williamson, G. (2002) Quercetin metabolism in the lens: role in inhibition of hydrogen peroxide induced cataract. Free Radical Biology and Medicine, 33. pp. 63-70.

D

Di Gesso, Jessica, Kerr, Jason, Zhang, Qingzhi, Raheem, Saki, Krishna Yalamanchili, Sai, O'Hagan, David, Kay, Colin and O'Connell, Maria (2015) Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes. Molecular Nutrition & Food Research, 59 (6). 1143–1154. ISSN 1613-4125

E

Ekstrom, E. J., Sherwood, V. and Andersson, T. (2011) Methylation and Loss of Secreted Frizzled-Related Protein 3 Enhances Melanoma Cell Migration and Invasion. PLoS ONE, 6 (4). ISSN 1932-6203

G

Guha, M., O'Connell, M. A., Pawlinski, R., Hollis, A., McGovern, P., Yan, S. F., Stern, D. and Mackman, N. (2001) Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood, 98 (5). pp. 1429-1439. ISSN 0006-4971

H

Howell, LA, Waller, Z.A.E., Bowater, RP, O'Connell, M and Searcey, M (2011) A small molecule that induces assembly of a four way DNA junction at low temperature. Chemical Communications, 47 (29). pp. 8262-8264. ISSN 1359-7345

Howell, Lesley, Gulam, R, Mueller, Anja, O'Connell, Maria and Searcey, Mark (2010) Design and synthesis of threading intercalators to target DNA. Bioorganic & Medicinal Chemistry Letters, 1 (20). pp. 6956-6959. ISSN 1464-3405

Howell, Lesley, Howman, Aaron, O'Connell, Maria, Mueller, Anja and Searcey, Mark (2009) Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry. Bioorganic & Medicinal Chemistry Letters, 19 (20). pp. 5880-5883. ISSN 1464-3405

Howell, Lesley A., Bowater, Richard A., O'Connell, Maria A., Reszka, Anthony P., Neidle, Stephen and Searcey, Mark (2012) Synthesis of Small Molecules Targeting Multiple DNA Structures using Click Chemistry. ChemMedChem, 7 (5). pp. 792-804. ISSN 1860-7179

J

Jacques, Richard O., Mills, Shirley C., Cazzonatto Zerwes, Paula, Fagade, Feyisope O., Green, John E., Downham, Scott, Sexton, Darren W. and Mueller, Anja (2015) Dynamin function is important for CC-chemokine receptor induced cell migration. Cell Biochemistry and Function, 33 (6). pp. 407-414. ISSN 0263-6484

Jenei, V., Sherwood, V., Howlin, J., Linnskog, R., Safholm, A., Axelsson, L. and Andersson, T. (2009) A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion. Proceedings of the National Academy of Sciences, 106 (46). pp. 19473-19478. ISSN 0027-8424

K

Khabbazi, S., Jacques, R.O., Moyano Cardaba, C. and Mueller, A. (2013) Janus kinase 2 and signal transducer and activator of transcription 3 activation is not essential for CCL3-, CCL5- or CCL8-induced chemotaxis. Cell Biochemistry and Function, 31 (4). pp. 312-318. ISSN 0263-6484

L

Lee, Hannah Y. Y., Morton, James D., Sanderson, Julie, Bickerstaffe, Roy and Robertson, Lucinda J. G. (2008) The involvement of calpains in opacification induced by Ca2+-overload in ovine lens culture. Veterinary Ophthalmology, 11 (6). pp. 347-355. ISSN 1463-5224

Liu, R, O'Connell, M, Johnson, K, Pritzker, K, Mackman, N and Terkeltaub, R (2000) Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells. Arthritis & Rheumatism, 43 (5). pp. 1145-1155. ISSN 0004-3591

M

Mills, Shirley C., Goh, Poh Hui, Kudatsih, Jossie, Ncube, Sithembile, Gurung, Renu, Maxwell, Will and Mueller, Anja (2016) Cell migration towards CXCL12 in leukemic cells compared to breast cancer cells. Cellular Signalling, 28 (4). pp. 316-324. ISSN 0898-6568

Mishra, Gita D, McNaughton, Sarah A, O'Connell, Maria, Prynne, Celia J and Kuh, Diana (2009) Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohort. Public Health Nutrition, 12 (02). p. 166. ISSN 1475-2727

Moore, S. E., Falorni, A., Bini, V., Fulford, A. J. C., O'Connell, M. A. and Prentice, A. M. (2004) Ethnic differences in the relationship between fasting leptin and BMI in children. International Journal of Obesity, 28 (1). pp. 17-21. ISSN 0307-0565

Moore, S. E., Morgan, G., Collinson, A. C., Swain, J. A., O'Connell, M. A. and Prentice, A. M. (2002) Leptin, malnutrition, and immune response in rural Gambian children. Archives of Disease in Childhood, 87 (3). pp. 192-197. ISSN 0003-9888

Moyano, C, Jacques, RO, Barrett, JE, Hassell, KM, Kavanagh, A, Remington, FC, Tse, T and Mueller, A (2012) CCL3 induced migration occurs independently of intracellular calcium release. Biochemical and Biophysical Research Communications, 418 (1). pp. 17-21. ISSN 1090-2104

Mueller, A. (2007) Internalization: what does it tell us about pharmacokinetic and pharmacodynamic properties of an antagonist? British Journal of Pharmacology, 152 (8). pp. 1145-1146. ISSN 0007-1188

Mueller, A., Kelly, E. and Strange, P. G. (2002) Pathways for internalization and recycling of the chemokine receptor CCR5. Blood, 99 (3). pp. 785-791. ISSN 0006-4971

Mueller, A., Mahmoud, N. G., Goedecke, M. C., McKeating, J. A. and Strange, P. G. (2002) Pharmacological characterization of the chemokine receptor, CCR5. British Journal of Pharmacology, 135 (4). pp. 1033-1043. ISSN 0007-1188

Mueller, A., Mahmoud, N. G. and Strange, P. G. (2006) Diverse signalling by different chemokines through the chemokine receptor CCR5. Biochemical Pharmacology, 72 (6). pp. 739-748. ISSN 0006-2952

Mueller, A. and Strange, P. G. (2004) CCL3, acting via the chemokine receptor CCR5, leads to independent activation of Janus kinase 2 (JAK2) and G(i) proteins. FEBS Letters, 570 (1-3). pp. 126-132. ISSN 0014-5793

Mueller, A. and Strange, P. G. (2004) Mechanisms of internalization and recycling of the chemokine receptor, CCR5. European Journal of Biochemistry, 271 (2). pp. 243-252. ISSN 0014-2956

Mueller, A. and Strange, P. G. (2004) The chemokine receptor, CCR5. International Journal of Biochemistry & Cell Biology, 36 (1). pp. 35-38. ISSN 1357-2725

N

Niyadurupola, N, Sidaway, P, Osborne, A, Broadway, D and Sanderson, J (2011) The development of human organotypic retinal cultures (HORCs) to study retinal neurodegeneration. British Journal of Ophthalmology, 10. pp. 720-726. ISSN 0007-1161

Niyadurupola, N., Sidaway, P., Ma, N., Sanderson, Julie, Broadway, D.C. and Rhodes, J.D. (2013) P2X7 receptor activation mediates retinal ganglion cell death in a human retina model of ischemic neurodegeneration. Investigative Ophthalmology & Visual Science, 54 (3). pp. 2163-2170. ISSN 0146-0404

Norton, R and O'Connell, MA (2012) Vitamin D: Potential in the prevention and treatment of lung cancer. Anticancer Research, 32. pp. 211-222. ISSN 1791-7530

O

O'Connell, M A, Bennett, B L, Mercurio, F, Manning, A M and Mackman, N (1998) Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells. Journal of Biological Chemistry, 273 (46). pp. 30410-30414. ISSN 0021-9258

O'Connell, Maria and Rushworth, Stuart (2008) Curcumin: potential for hepatic fibrosis therapy? British Journal of Pharmacology, 153 (3). pp. 403-405. ISSN 1476-5381

O'Connell, Maria, Weir, Donald and Kelleher, Dermot (1994) Tumour necrosis factor and cachexia in chronic inflammatory bowel disease. European Journal of Gastroenterology & Hepatology, 6. pp. 821-829. ISSN 0954-691X

Ogborne, R. M., Rushworth, S. A., Charalambos, C. A. and O'Connell, M. A. (2004) Haem oxygenase-1: a target for dietary antioxidants. Biochemical Society Transactions, 32. pp. 1003-1005. ISSN 0300-5127

Ogborne, R. M., Rushworth, S. A. and O'Connell, M. A. (2005) alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 25 (10). pp. 2100-2105. ISSN 1079-5642

Ogborne, Richard M., Rushworth, Stuart and O'Connell, Maria (2008) Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cδ and Nrf2. Biochemical and Biophysical Research Communications, 373 (4). pp. 584-588. ISSN 1090-2104

Osborne, Andrew, Hopes, Marina, Wright, Phillip, Broadway, David C. and Sanderson, Julie (2016) Human organotypic retinal cultures (HORCs) as a chronic experimental model for investigation of retinal ganglion cell degeneration. Experimental Eye Research, 143. pp. 28-38. ISSN 0014-4835

P

Prentice, A. M., Moore, S. E., Collinson, A. C. and O'Connell, M. A. (2002) Leptin and undernutrition. Nutrition Reviews, 60 (10). S56-S67. ISSN 0029-6643

Prudlo, J., Fischer, A., Lapple, M., Mueller, A., Neubert, K., Gericke, C. A., Ludolph, A. C., Grasser, F. and Sauder, C. (2002) Seroprevalence of Borna disease virus antibodies is not increased in patients with amyotrophic lateral sclerosis. Journal of Neurology, 249 (10). pp. 1462-1463. ISSN 0340-5354

Prynne, Celia J., Mishra, Gita D., O'Connell, Maria A., Muniz, Graciela, Laskey, M. Ann, Yan, Liya, Prentice, Ann and Ginty, Fiona (2006) Fruit and vegetable intakes and bone mineral status: a cross-sectional study in 5 age and sex cohorts. American Journal of Clinical Nutrition, 83 (6). pp. 1420-1428. ISSN 0002-9165

R

Radreau, P, Rhodes, JD, Mithen, RC, Kroon, PA and Sanderson, J (2009) Hypoxia-inducible factor-1 (HIF-1) pathway activation by quercetin in human lens epithelial cells. Experimental Eye Research, 89 (6). pp. 995-1002. ISSN 1096-0007

Recino, A., Sherwood, V., Flaxman, A., Cooper, W. N., Latif, F., Ward, A. and Chalmers, A. D. (2010) Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. Biochemical Journal, 430. pp. 207-213. ISSN 0264-6021

Redshaw, C, Elsegood, MRJ, Frese, JWA, Ashby, S, Chao, Y and Mueller, A (2012) Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopy. Chemical Communications, 48 (53). pp. 6627-6629. ISSN 1359-7345

Redshaw, C, Elsegood, MRJ, Wright, JA, Baillie-Johnson, H, Yamato, T, Giovanni, SD and Mueller, A (2012) Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arene. Chemical Communications, 48 (8). pp. 1129-1131. ISSN 1359-7345

Redshaw, Carl, Watkins, Scott, Humphrey, Simon M., Bulman Page, Philip C., Ashby, Shane, Chao, Yimin, Herbert, Christopher J. and Mueller, Anja (2013) Rhenium(I) phenanthrolines bearing electron withdrawing CF3 substituents: synthesis, characterization and biological evaluation. RSC Advances, 3 (46). pp. 23963-23966. ISSN 2046-2069

Rhodes, JD, Lott, MC, Russell, SL, Moulton, V, Sanderson, J, Wormstone, IM and Broadway, DC (2012) Activation of the innate immune response and interferon signalling in myotonic dystrophy type 1 and type 2 cataracts. Human Molecular Genetics, 21 (4). pp. 852-862. ISSN 1460-2083

Rhodes, JD and Sanderson, J (2009) The mechanisms of calcium homeostasis and signalling in the lens. Experimental Eye Research, 88 (2). pp. 226-234. ISSN 1096-0007

Robbins, D, Newton, AF, Gignoux, C, Legeay, J-C, Sinclair, A, Rejzek, M, Laxon, CA, Lewis, W, Yalamanchili, S, O'Connell, MA and Stockman, RA (2011) Synthesis of natural-product-like scaffolds in unprecedented efficiency via a 12-fold branching pathway. Chemical Science, 11 (2). pp. 2232-2235. ISSN 2041-6539

Rushworth, S. A., Chen, X. L., Mackman, N., Ogborne, R. M. and O'Connell, M. A. (2005) Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. Journal of Immunology, 175 (7). pp. 4408-4415. ISSN 0022-1767

Rushworth, S. A. and O'Connell, M. A. (2004) Haem oxygenase-1 in inflammation. Biochemical Society Transactions, 32. pp. 1093-1094. ISSN 0300-5127

Rushworth, S. A., Ogborne, R. M., Charalambos, C. A. and O'Connell, M. A. (2006) Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. Biochemical and Biophysical Research Communications, 341 (4). pp. 1007-1016. ISSN 0006-291X

S

Sanderson, J., Marcantonio, J. M. and Duncan, G. (2000) A human lens model of cortical cataract: Ca2+-induced protein loss, vimentin cleavage and opacification. Investigative Ophthalmology & Visual Science, 41 (8). pp. 2255-2261. ISSN 0146-0404

Sherwood, V., Burgert, H. G., Chen, Y. H., Sanghera, S., Katafigiotis, S., Randall, R. E., Connerton, I. and Mellits, K. H. (2007) Improved growth of enteric adenovirus type 40 in a modified cell line that can no longer respond to interferon stimulation. Journal of General Virology, 88. pp. 71-76. ISSN 0022-1317

Sherwood, V., Manbodh, R., Sheppard, C. and Chalmers, A. D. (2008) RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Molecular Biology of the Cell, 19 (4). pp. 1772-1782. ISSN 1059-1524

Sherwood, V., Recino, A., Jeffries, A., Ward, A. and Chalmers, A. D. (2010) The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation. Biochemical Journal, 425. pp. 303-311. ISSN 0264-6021

Sherwood, Victoria, Chaurasiya, Shivendra Kumar, Ekström, Elin J, Guilmain, William, Liu, Qing, Koeck, Thomas, Brown, Kate, Hansson, Karin, Agnarsdóttir, Margrét, Bergqvist, Michael, Jirström, Karin, Ponten, Fredrik, James, Peter and Andersson, Tommy (2014) WNT5A-Mediated β-Catenin-Independent Signalling is a Novel Regulator of Cancer Cell Metabolism. Carcinogenesis, 35 (4). pp. 784-794. ISSN 0143-3334

Sherwood, Victoria, Di Silvio, Desire and Baldelli Bombelli, Francesca (2014) Nanoscopic Agents in a Physiological Environment: The Importance of Understanding Their Characteristics. In: Personalized Medicine with a Nanochemistry Twist. Topics in Medicinal Chemistry . Springer, pp. 29-54. ISBN 978-3-319-33544-5

Sherwood, Victoria, King, Elizabeth, Tötemeyer, Sabine, Connerton, Ian and Mellits, Kenneth H (2012) Interferon treatment suppresses enteric adenovirus infection in a model gastrointestinal cell-culture system. Journal of General Virology, 93 (3). pp. 618-623. ISSN 0022-1317

Steel, R, Cowan, J, Payerne, E, O'Connell, MA and Searcey, M (2012) Anti-inflammatory effect of a cell penetrating peptide targeting the Nrf2/Keap1 interaction. ACS Medicinal Chemistry Letters, 3. pp. 407-410. ISSN 1948-5875

T

Tortorici, Marcello, Borrello, Maria Teresa, Tardugno, Maria, Chiarelli, Laurent R, Pilotto, Simona, Ciossani, Giuseppe, Vellore, Nadeem A, Bailey, Sarah G, Cowan, Jonathan, O'Connell, Maria, Crabb, Simon J, Packham, Graham, Mai, Antonello, Baron, Riccardo, Ganesan, A and Mattevi, Andrea (2013) Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase. ACS Chemical Biology, 8 (8). pp. 1677-1682. ISSN 1554-8937

Tovell, Victoria and Sanderson, Julie (2008) Distinct P2Y Receptor Subtypes Regulate Calcium Signaling in Human Retinal Pigment Epithelial Cells. Investigative Ophthalmology & Visual Science, 49 (1). pp. 350-357. ISSN 0146-0404

Tröβe, C, Rhodes, JD, Sanderson, J, Breck, O and Waagbø, R (2010) Effect of plant-based feed ingredients on osmoregulation in the Atlantic salmon lens. Comparative Biochemistry and Physiology - Part B Biochemistry & Molecular Biology, 155 (4). pp. 354-362.

W

Waller, Zoë A E, Howell, Lesley A, Macdonald, Colin J, O'Connell, Maria A and Searcey, Mark (2014) Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2). Biochemical and Biophysical Research Communications, 447 (1). pp. 128-32. ISSN 0006-291X

Wang, L.X., Prescott, A.R., Spruce, B.A., Sanderson, J and Duncan, G (2005) Sigma receptor antagonists inhibit human lens cell growth and induce pigmentation. Investigative Ophthalmology and Visual Science, 46. pp. 1403-1408. ISSN 1552-5783

Wang, Lixin, Eldred, Julie A, Sidaway, Peter, Sanderson, Julie, Smith, Andrew J. O., Bowater, Richard P, Reddan, John R and Wormstone, I Michael (2012) Sigma 1 receptor stimulation protects against oxidative damage through suppression of the ER stress responses in the human lens. Mechanisms of Ageing and Development, 133 (11-12). pp. 665-674. ISSN 0047-6374

Webster, Carl, Di Silvio, Desire, Devarajan, Aarthi, Bigini, Paolo, Micotti, Eduardo, Giudice, Chiari, Salmona, Mario, Wheeler, Grant, Sherwood, Victoria and Baldelli Bombelli, Francesca (2016) An early developmental vertebrate model for nanomaterial safety:bridging cell-based and mammalian toxicity assessment. Nanomedicine, 11 (6). pp. 643-656. ISSN 1743-5889

This list was generated on Sun Mar 24 20:17:14 2019 GMT.