Items where Author is "Alshaker, Heba"

Published

Hunter, Ewan, Alshaker, Heba, Weston, Cicely, Issa, Mutaz, Bautista, Shekinah, Gebregzabhar, Abel, Virdi, Anya, Dring, Ann, Powell, Ryan, Green, Jayne, Lal, Roshan, Velchuru, Vamsi, Aryal, Kamal, Bin Abu Hassan, Muhammad Radzi, Meng, Goh Tiong, Patel, Janisha Suriakant, Mohamed Gani, Shameera Pharveen, Lim, Chun Ren, Guiel, Thomas, Akoulitchev, Alexandre and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2025) A new blood-bBased epigenetic diagnostic biomarker test (EpiSwitch®® NST) with high sensitivity and positive predictive value for colorectal cancer and precancerous polyps. Cancers, 17 (3). ISSN 2072-6694

Hunter, Ewan, Salter, Matthew, Powell, Ryan, Dring, Ann, Naithani, Tarun, Chatziioannou, Maria Eleni, Gebregzabhar, Abel, Issa, Mutaz, Green, Jayne, Ng, Serene, Lim, Chun Ren, Keat, Cheah Soon, Suan, Ang Tick, Raman, Rakesh, Fatt, Ho Kean, Luen, Fabian Lee Wei, Alshaker, Heba, Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261, Blum, Dave, Guiel, Thomas, Heaton, Robert, Levine, Jedd and Akoulitchev, Alexandre (2023) Development and validation of blood-based predictive biomarkers for response to PD-1/PD-L1 checkpoint inhibitors: Evidence of a universal systemic core of 3D immunogenetic profiling across multiple oncological indications. Cancers, 15 (10). ISSN 2072-6694

Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261, Hunter, Ewan, Dezfouli, Mehrnoush, Salter, Matthew, Powell, Ryan, Green, Jayne, Naithani, Tarun, Koutsothanasi, Christina, Alshaker, Heba, Jaipuria, Jiten, Connor, Martin J., Eldred-Evans, David, Fiorentino, Francesca, Ahmed, Hashim, Akoulitchev, Alexandre and Winkler, Mathias (2023) Circulating chromosome conformation signatures significantly enhance PSA positive predicting value and overall accuracy for prostate cancer detection. Cancers, 15 (3). ISSN 2072-6694

Alshaker, Heba, Hunter, Ewan, Salter, Matthew, Ramadass, Aroul, Westra, Willem, Winkler, Mathias, Green, Jayne, Akoulitchev, Alexandre and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2022) Monocytes acquire prostate cancer specific chromatin conformations upon indirect co-culture with prostate cancer cells. Frontiers in Oncology, 12. ISSN 2234-943X

Alshaker, Heba, Mills, Robert, Hunter, Ewan, Salter, Matthew, Ramadass, Aroul, Skinner, Benjamin Matthew, Westra, Willem, Green, Jayne, Akoulitchev, Alexandre, Winkler, Mathias and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2021) Chromatin conformation changes in peripheral blood can detect prostate cancer and stratify disease risk groups. Journal of Translational Medicine, 19 (1). ISSN 1479-5876

Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261, Alshaker, Heba, Babovic, Radomir and Maw, Kyaw (2021) A case of severe dry eye disease with corneal melting as presenting complaint of acute myeloid leukaemia. SAGE Open Medical Case Reports, 9. ISSN 2050-313X

Alshaker, Heba, Thrower, Hannah and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2020) Sphingosine kinase 1 in breast cancer: A new molecular marker and a therapy target. Frontiers in Oncology, 10. ISSN 2234-943X

Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261, Kenbaz, Mojiba, Alshaker, Heba and Jesudason, Kiruparajan (2020) Bradycardia and syncope as sole manifestations of a cranial lesion: a case report. Journal of Medical Case Reports, 14 (1). ISSN 1752-1947

Alshaker, Heba, Wang, Qi, Brewer, Daniel ORCID: https://orcid.org/0000-0003-4753-9794 and Pshezhetskiy, Dmitry ORCID: https://orcid.org/0000-0003-1074-9261 (2019) Transcriptome-wide effects of sphingosine kinases knockdown in metastatic prostate and breast cancer cells: Implications for therapeutic targeting. Frontiers in Pharmacology, 10. ISSN 1663-9812

Alshaker, Heba, Srivats, Shyam, Monteil, Danielle, Wang, Qi, Low, Caroline M. R. and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2018) Field template-based design and biological evaluation of new sphingosine kinase 1 inhibitors. Breast Cancer Research and Treatment, 172 (1). 33–43. ISSN 0167-6806

Alshaker, Heba, Wang, Qi, Srivats, Shyam, Chao, Yimin ORCID: https://orcid.org/0000-0002-8488-2690, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2017) New FTY720-docetaxel nanoparticle therapy overcomes FTY720-induced lymphopenia and inhibits metastatic breast tumour growth. Breast Cancer Research and Treatment, 165 (3). 531–543. ISSN 0167-6806

Wang, Qi, Alshaker, Heba, Böhler, Torsten, Srivats, Shyam, Chao, Yimin ORCID: https://orcid.org/0000-0002-8488-2690, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2017) Core shell lipid-polymer hybrid nanoparticles with combined docetaxel and molecular targeted therapy for the treatment of metastatic prostate cancer. Scientific Reports, 7. ISSN 2045-2322

Alshaker, Heba, Wang, Qi, Böhler, Torsten, Mills, Robert, Winkler, Mathias, Arafat, Tawfiq, Kawano, Yoshiaki and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2017) Combination of RAD001 (everolimus) and docetaxel reduces prostate and breast cancer cell VEGF production and tumour vascularisation independently of sphingosine-kinase-1. Scientific Reports, 7. ISSN 2045-2322

Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261, Kenbaz, Mojiba, Alshaker, Heba, Rajput, Dharmesh and Jesudason, Kiruparajan (2017) An unusual case of disseminated intravascular coagulation. Oxford Medical Case Reports, 2017 (4).

Alshaker, Heba, Wang, Qi, Kawano, Yoshiaki, Arafat, Tawfiq, Böhler, Torsten, Winkler, Mathias, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042 and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2016) Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1. Oncotarget, 7 (49). pp. 80943-80956. ISSN 1949-2553

Sacco, Keith, Muhammad, Aun, Saleem, Waqar, Alshaker, Heba, Monzon, Leonardo, Islam, Mohammad Rafiqul and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2016) Leptomeningeal carcinomatosis as the primary presentation of relapse in breast cancer. Oncology Letters, 12 (2). pp. 779-782. ISSN 1792-1074

White, Christopher, Alshaker, Heba, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Winkler, Matthias and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2016) The emerging role of FTY720 (Fingolimod) in cancer treatment. Oncotarget, 7 (17). pp. 23106-23127. ISSN 1949-2553

Alshaker, Heba, Sacco, Keith, Alfraidi, Albandri, Muhammad, Aun, Winkler, Mathias and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2015) Leptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemma. Oncotarget, 6 (34). pp. 35556-35563. ISSN 1949-2553

Alshaker, Heba, Wang, Qi, Frampton, Adam E., Krell, Jonathan, Waxman, Jonathan, Winkler, Mathias, Stebbing, Justin, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Yaguee, Ernesto and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2015) Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer. Breast Cancer Research and Treatment, 149 (1). pp. 59-67. ISSN 1573-7217

Alshaker, Heba, Krell, Jonathan, Frampton, Adam E., Wang, Qi, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Winkler, Mathias, Yaguee, Ernesto, Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 and Alshaker, Heba (2015) Leptin receptor-dependent and -independent STAT3 phosphorylation in oestrogen receptor-negative breast cancer. International Journal of Molecular Medicine, 36. S6. ISSN 1107-3756

Alshaker, Heba, Krell, Jonathan, Frampton, Adam E., Waxman, Jonathan, Blyuss, Oleg, Zaikin, Alexey, Winkler, Mathias, Stebbing, Justin, Yaguee, Ernesto and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2014) Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway. Breast Cancer Research, 16. ISSN 1465-542X

Pshezhetskiy, Dmitry ORCID: https://orcid.org/0000-0003-1074-9261, Alshaker, Heba and Stebbing, Justin (2014) Castrate-resistant prostate cancer: the future of antiandrogens. Trends in Urology & Men’s Health, 5 (1). ISSN 2044-3749

Pinho, Filipa G., Frampton, Adam E., Nunes, Joao, Krell, Jonathan, Alshaker, Heba, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, de Giorgio, Alexander, Harding, Victoria, Waxman, Jonathan, Stebbing, Justin, Pchejetski, Dmitry and Castellano, Leandro (2013) Downregulation of microRNA-515-5p by the estrogen receptor modulates Sphingosine Kinase 1 and breast cancer cell proliferation. Cancer Research, 73 (19). pp. 5936-5948. ISSN 0008-5472

Alshaker, Heba, Sauer, Lysann, Monteil, Danielle, Ottaviani, Silvia, Srivats, Shyam, Böhler, Torsten and Pchejetski, Dmitri ORCID: https://orcid.org/0000-0003-1074-9261 (2013) Chapter Six – Therapeutic Potential of Targeting SK1 in Human Cancers. In: Advances in Cancer Research. Advances in Cancer Research, 117 . Elsevier, pp. 143-200. ISBN 978-0-12-394274-6