Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase

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Field, Robert A. ORCID: https://orcid.org/0000-0001-8574-0275, Neville, David C. A., Smith, Roland W. and Ferguson, Michael A. J. (1994) Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase. Bioorganic and Medicinal Chemistry Letters, 4 (3). pp. 391-394. ISSN 0960-894X

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Abstract

A series of 4- and 6-substituted derivatives of benzyl N-acetyl-β-D-glucosaminide were prepared and assessed as inhibitors of bovine β-1,4-galactosyl transferase. Of the azido, amino, and acetamido compounds tested, only the 4-amino compound (2) produced significant inhibition of this enzyme.

Item Type:	Article
Uncontrolled Keywords:	biochemistry,molecular medicine,molecular biology,pharmaceutical science,drug discovery,clinical biochemistry,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1300/1303
Faculty \ School:	Faculty of Science > School of Chemistry, Pharmacy and Pharmacology
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	11 Sep 2024 14:30
Last Modified:	25 Sep 2024 18:09
URI:	https://ueaeprints.uea.ac.uk/id/eprint/96721
DOI:	10.1016/0960-894X(94)80002-2

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