Electronic cigarettes and subsequent use of cigarettes in young people: An evidence and gap map

Conde, Monserrat, Tudor, Kate, Begh, Rachna, Nolan, Rebecca, Zhu, Sufen, Kale, Dimitra, Jackson, Sarah, Livingstone-Banks, Jonathan, Lindson, Nicola, Notley, Caitlin ORCID: https://orcid.org/0000-0003-0876-3304, Hastings, Janna, Cox, Sharon, Pesko, Michael F., Thomas, James and Hartmann-Boyce, Jamie (2024) Electronic cigarettes and subsequent use of cigarettes in young people: An evidence and gap map. Addiction. ISSN 0965-2140

[thumbnail of final published paper_addiction_06-2024]
PDF (final published paper_addiction_06-2024) - Published Version
Available under License Creative Commons Attribution Non-commercial.

Download (8MB) | Preview


Background and aims: The use of e-cigarettes may influence later smoking uptake in young people. Evidence and gap maps (EGMs) are interactive on-line tools that display the evidence and gaps in a specific area of policy or research. The aim of this study was to map clusters and gaps in evidence exploring the relationship between e-cigarette use or availability and subsequent combustible tobacco use in people aged < 30 years.   Methods: We conducted an EGM of primary studies and systematic reviews. A framework and an interactive EGM was developed in consultation with an expert advisory group. A systematic search of five databases retrieved 9057 records, from which 134 studies were included. Systematic reviews were appraised using AMSTAR-2, and all included studies were coded into the EGM framework resulting in the interactive web-based EGM. A descriptive analysis of key characteristics of the identified evidence clusters and gaps resulted in this report.   Results: Studies were completed between 2015 and 2023, with the first systematic reviews being published in 2017. Most studies were conducted in western high-income countries, predominantly the United States. Cohort studies were the most frequently used study design. The evidence is clustered on e-cigarette use as an exposure, with an absolute gap identified for evidence looking into the availability of e-cigarettes and subsequent cessation of cigarette smoking. We also found little evidence analysing equity factors, and little exploring characteristics of e-cigarette devices.   Conclusions: This evidence and gap map (EGM) offers a tool to explore the available evidence regarding the e-cigarette use/availability and later cigarette smoking in people under the age of 30 years at the time of the search. The majority of the 134 reports is from high-income countries, with an uneven geographic distribution. Most of the systematic reviews are of lower quality, suggesting the need for higher-quality reviews. The evidence is clustered around e-cigarette use as an exposure and subsequent frequency/intensity of current combustible tobacco use. Gaps in evidence focusing on e-cigarette availability, as well as on the influence of equity factors may warrant further research. This EGM can support funders and researchers in identifying future research priorities, while guiding practitioners and policymakers to the current evidence base.

Item Type: Article
Additional Information: Research Funding: Cancer Research UK. Grant Number: PPRCTAGPJT\100002
Uncontrolled Keywords: cigarettes,electronic cigarettes,evidence and gap map,smoking,vaping,young people,youth,psychiatry and mental health,medicine (miscellaneous),sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2738
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 02 Jul 2024 16:32
Last Modified: 15 Jul 2024 08:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/95766
DOI: 10.1111/add.16583


Downloads per month over past year

Actions (login required)

View Item View Item